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merck millipore,默克密理博,MAB1614,Anti-Kinesin Antibody, heavy chain, a.a.420-445, clone H2
产品名称：Anti-Kinesin Antibody, heavy chain, a.a.420-445, clone H2
产品型号：MAB1614
Detect Kinesin using this Anti-Kinesin Antibody, heavy chain, a.a.420-445, clone H2 validated for use in ELISA, IC, IH, IP, FUNC, RIA & WB.
merck millipore,默克密理博,MAB1614,Anti-Kinesin Antibody, heavy chain, a.a.420-445, clone H2
- 产品介绍
重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 R, Ch, Ma, Sqd, Su, H, M WB, ELISA, ICC, IHC M Purified Monoclonal Antibody 描述 产品目录编号 MAB1614 品牌系列 Chemicon®
商名 - Chemicon
描述 Anti-Kinesin Antibody, heavy chain, a.a.420-445, clone H2 背景信息 Kinesins are molecular motors used for intracellular transport and trafficking. They move along microtubule cables powered by the hydrolysis of ATP, thus kinesins are ATPases. The active movement of kinesins supports several cellular functions including mitosis, meiosis and transport of cargo such as axonal transport. 产品信息 格式 Purified 控制 - Brain tissue
演示 Purified mouse monoclonal IgG2b in buffer containing 0.02 M Phosphate buffer, 0.25 M NaCl with 0.1% sodium azide. 应用 应用 Detect Kinesin using this Anti-Kinesin Antibody, heavy chain, a.a.420-445, clone H2 validated for use in ELISA, IC, IH, IP, FUNC, RIA & WB. 主要应用 - Western Blotting
- ELISA
- Immunocytochemistry
- Immunohistochemistry
应用说明 Immunohistochemistry:
A previous lot was used on paraformaldehyde fixed tissue. Also works for EM.
Immunocytochemistry:
A previous lot of this antibody was used in Immunocytochemistry.
Immunoprecipitation:
A previous lot of this antibody was used in Immunoprecipitation.
EIA/RIA:
A previous lot of this antibody was used in RIA.
Immunoblotting: recognizes 124kDa KHC and its proteolytic fragments.
Inhibition of kinesin mediated transport {Brady, et al PNAS 87(3):1061-1065, 1990.
Optimal working dilutions must be determined by the end user.生物信息 免疫原品种 Bovine brain kinesin. 表位 a.a.420-445 克隆 H2 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Mouse 特异性 Reacts with the heavy chain of kinesin near the N-terminus. 同种型 IgG2b 品种反应性 RatChickenMammalsSquidSea UrchinHumanMouse Species Reactivity Note Reactive with all mammals, chicken, squid, sea urchins and clams. 抗体类型 Monoclonal Antibody Entrez基因编号 - NP_004512
基因符号 - KNS
- KIF5B
- UKHC
- KINH
- KNS1
纯化方法 Protein A purfied UniProt编号 - P33176
UniProt汇总 FUNCTION: SwissProt: P33176 # Microtubule-dependent motor required for normal distribution of mitochondria and lysosomes (By similarity).
SIZE: 963 amino acids; 109685 Da
SUBUNIT: Oligomer composed of two heavy chains and two light chains. Interacts with GRIP1 (By similarity). Interacts with SYBU.
SUBCELLULAR LOCATION: Note=Uniformly distributed between soma and neurites in hippocampal neurons (By similarity).
DOMAIN: SwissProt: P33176 Composed of three structural domains: a large globular N- terminal domain which is responsible for the motor activity of kinesin (it hydrolyzes ATP and binds microtubule), a central alpha-helical coiled coil domain that mediates the heavy chain dimerization; and a small globular C-terminal domain which interacts with other proteins (such as the kinesin light chains), vesicles and membranous organelles.
SIMILARITY: Belongs to the kinesin-like protein family. Kinesin subfamily. & Contains 1 kinesin-motor domain.产品使用声明 质量保证 Routinely evaluated by Western Blot on Mouse Brain lysates.
Western Blot Analysis:
1:500 dilution of this lot detected KINESIN (HEAVY CHAIN) on 10 μg of Mouse Brain lysates.使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 6 months at 2-8°C in undiluted aliquots from date of receipt. 包装信息 数量 100 µg
上一件merck millipore产品：merck millipore,默克密理博,14-532,MEK2 Protein, unactive, 50 µg
下一件merck millipore产品：merck millipore,默克密理博,407317,Anti-Integrin β₆ Mouse mAb (442.5C4)
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