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- merck millipore,默克密理博,ABS310,Anti-hCE-1 Antibody
重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 H WB Rb Serum Polyclonal Antibody 描述 产品目录编号 ABS310 描述 Anti-hCE-1 Antibody Alternate Names - TGH
- Carboxylesterase 1
- Liver carboxylesterase 1
- Acyl-coenzyme A:cholesterol acyltransferase
- ACAT
- Brain carboxylesterase hBr1
- CE-1
- hCE-1
- Cocaine carboxylesterase
- Egasyn
- HMSE
- Methylumbelliferyl-acetate deacetylase 1
- Monocyte/macrophage serine esterase
- Retinyl ester hydrolase
- REH
- Serine esterase 1
- Triacylglycerol hydrolase
背景信息 Carboxylesterase 1 (hCE-1) is also known as Liver carboxylesterase 1, Acyl-coenzyme A:cholesterol acyltransferase, (ACAT), Cocaine carboxylesterase, Methylumbelliferyl-acetate deacetylase 1, Monocyte/macrophage serine esterase, Retinyl ester hydrolase, (REH), Serine esterase 1, and Triacylglycerol hydrolase (TGH). hCE-1 is involved in: the detoxification of xenobiotics and the activation of ester and amide prodrugs. hCE-1 functions to hydrolize the methyl ester group of cocaine to form benzoylecgonine, catalyze the transesterification of cocaine to form cocaethylene and the ethyl esterification of oleic acid to ethyloleate, and is activated by CHAPS. hCE-1 is expressed mostly in liver with lower levels found in the heart and lung. 产品信息 格式 Serum 控制 - HepG2 cell lysate
演示 Rabbit polyclonal serum with 0.05% sodium azide. 应用 应用 Detect Carboxylesterase 1 using this rabbit polyclonal antibody, Anti-hCE-1 Antibody validated for use in western blotting. 主要应用 - Western Blotting
应用说明 Western Blotting Analysis: A 1:1,000 dilution from a representative lot detected hCE-1 in 10 µg of human liver tissue lysate.
Western Blotting Analysis: A representative lot from an independent laboratory detected hCE-1 in hCE-1 transfected U373MG cell lysates, and demonstrated a loss of signal in non-transfected and hCE-2 transfected U373MG cell lysates (Prof. P. Potter, St. Jude Children's Research Hospital, Memphis.).生物信息 免疫原品种 Linear peptide corresponding to human hCE-1. 宿主 Rabbit 特异性 This antibody does not cross react with human CE-2 (Prof. P. Potter, St. Jude Children's Research Hospital, Memphis). 品种反应性 Human 抗体类型 Polyclonal Antibody Entrez基因编号 -
">NP_001020365.1
基因符号 - SES1
- CES1
- CES2
纯化方法 Unpurified UniProt编号 - P23141
产品使用声明 质量保证 Evaluated by Western Blotting in HepG2 cell lysate.
Western Blotting Analysis: A 1:1,000 dilution of this antibody detected hCE-1 in 10 µg of HepG2 cell lysate.使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at -20°C from date of receipt.
Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.包装信息 数量 100 µL
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