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  • merck millipore,默克密理博,17-493,PI3 Kinase Activity/Inhibitor ELISA

  • merck millipore,默克密理博,17-493,PI3 Kinase Activity/Inhibitor ELISA

    产品名称：PI3 Kinase Activity/Inhibitor ELISA
    产品型号：17-493
    This PI3 Kinase Activity/Inhibitor ELISA is used to measure & quantify PI 3-Kinase levels.

    merck millipore,默克密理博,17-493,PI3 Kinase Activity/Inhibitor ELISA

  • 产品介绍
  • merck millipore,默克密理博,17-493,PI3 Kinase Activity/Inhibitor ELISA

    重要规格表

    主要应用 可用的分析物 检测方法
    KAPI 3-KinaseHTRF, Colorimetric
    描述
    产品目录编号 17-493
    描述 PI3 Kinase Activity/Inhibitor ELISA
    产品信息
    部件
    • PI3K, p120γ
    • Glutathione-Coated Plate, 96-well strip format
    • 20% Tween® 20
    • 20X TBS Wash
    • Substrate TMB
    • Stop Buffer
    • SA-HRP Detection Reagent
    • GRP1-GST
    • Kinase Reaction Buffer, 5X
    • Wortmannin
    • PIP2
    • Biotinylated-PIP3
    • PI3K, p110α
    • PI3K, p110β
    • PI3K, p110δ
    检测方法 HTRFColorimetric
    应用
    应用 This PI3 Kinase Activity/Inhibitor ELISA is used to measure & quantify PI 3-Kinase levels.
    主要应用
    • Kinase Assay
    生物信息
    可用的分析物
    • PI 3-Kinase
    Entrez基因编号
    • NM_006218.2
    Entrez基因汇总 Phosphatidylinositol 3-kinase is composed of an 85 kDa regulatory subunit and a 110 kDa catalytic subunit. The protein encoded by this gene represents the catalytic subunit, which uses ATP to phosphorylate PtdIns, PtdIns4P and PtdIns(4,5)P2. This gene has been found to be oncogenic and has been implicated in cervical cancers.
    基因符号
    • PIK3CA
    • p110-alpha
    • MGC142161
    • PI3K
    • MGC142163
    UniProt编号
    • P42336
    UniProt汇总 FUNCTION: SwissProt: P42336 # Phosphorylates PtdIns, PtdIns4P and PtdIns(4,5)P2 with a preference for PtdIns(4,5)P2.
    SIZE: 1068 amino acids; 124284 Da
    SUBUNIT: Heterodimer of a p110 (catalytic) and a p85 (regulatory) subunit. Binds to IRS1 in nuclear extracts. Interacts with RUFY3 (By similarity).
    DISEASE: SwissProt: P42336 # Defects in PIK3CA are associated with colorectal cancer (CRC) [MIM:114500]. & Defects in PIK3CA are associated with breast cancer [MIM:114480]. & Defects in PIK3CA are associated with epithelial ovarian cancer (EOC) [MIM:604370].
    SIMILARITY: SwissProt: P42336 ## Belongs to the PI3/PI4-kinase family. & Contains 1 C2 domain. & Contains 1 PI3K/PI4K domain.
    产品使用声明
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    包装信息
    数量 1 plate
    包装 Kit capacity: 96 wells

    merck millipore,默克密理博,17-493,PI3 Kinase Activity/Inhibitor ELISA

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