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merck millipore,默克密理博,FCMAB408PE,Milli-Mark Anti-GABA A Receptor β2/3-PE Antibody, clone 62-3G1
产品名称:Milli-Mark Anti-GABA A Receptor β2/3-PE Antibody, clone 62-3G1
产品型号:FCMAB408PE
Milli-Mark Anti-GABA A Receptor β2/3-PE Antibody, clone 62-3G1 detects level of Milli-Mark GABA A Receptor β2/3-PE & has been published & validated for use in Flow Cytometry.
merck millipore,默克密理博,FCMAB408PE,Milli-Mark Anti-GABA A Receptor β2/3-PE Antibody, clone 62-3G1
- 产品介绍
重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 R FC M Phycoerythrin Monoclonal Antibody 描述 产品目录编号 FCMAB408PE 商名 - Milli-Mark
描述 Milli-Mark® Anti-GABA A Receptor β2/3-PE Antibody, clone 62-3G1 Alternate Names - gamma-aminobutyric acid A receptor, alpha 1
- GABA(A) receptor subunit alpha-1
- gamma-aminobutyric acid (GABA) A receptor, alpha 1
背景信息 The neurotransmitter GABA (gamma-aminobutyric acid) binds to specific transmembrane receptors in the plasma membrane of both pre- and postsynaptic neurons. Three general classes of GABA receptors are known: GABAA and GABAC (ionotropic) receptors and GABAB (metabotropic) receptors. The GABAA (gamma-Aminobutyric Acid type A) receptor is a multiprotein complex that acts as a ligand-gated chloride channel. These receptors are hetero-oligomers, for which 6 subunits are currently known (a, b, g, d, e and r). There are at least 3 different isoforms of the beta subunit, and receptor subunit expression varies during development. Additionally, GABAA receptors are important in regulating the reinforcing properties of alcohol, and expression of the alpha1 and beta 2/3 subunits increase upon chronic exposure to alcohol, and may be potential therapeutic targets for alcohol dependency. The beta 2 subunit is required for receptor assembly and surface expression, while mice with an inactivated beta3 subunit exhibit epilepsy and cleft palate. 产品信息 格式 Phycoerythrin 控制 - B35 cells
演示 Purified mouse monoclonal IgG1 conjugated to PE in PBS with 0.1% sodium azide and 15 mg/mL BSA. 应用 应用 Milli-Mark Anti-GABA A Receptor β2/3-PE Antibody, clone 62-3G1 detects level of Milli-Mark GABA A Receptor β2/3-PE & has been published & validated for use in Flow Cytometry. 主要应用 - Flow Cytometry
生物信息 免疫原品种 Affinity-purified GABAA receptor isolated from bovine brain. 克隆 62-3G1 宿主 Mouse 同种型 IgG1 品种反应性 Rat Species Reactivity Note Demonstrated to react with Rat. Predicted to react with Bovine based on immunogen design. 抗体类型 Monoclonal Antibody Entrez基因编号 - NP_000797.2
基因符号 - EJM
- GABRA1
- GABA
纯化方法 Protein G purified UniProt编号 - P14867
产品使用声明 质量保证 Evaluated by flow cytometry using B35 cells 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Maintain refrigerated at 2-8°C protected from light in undiluted aliquots for up to 6 months from date of receipt. 包装信息 数量 100 tests
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