merck millipore,默克密理愽
  • merck millipore,默克密理博,14-334M,PRAK Protein, active, 250 µg

  • merck millipore,默克密理博,14-334M,PRAK Protein, active, 250 µg

    产品名称：PRAK Protein, active, 250 µg
    产品型号：14-334M
    Active, N-terminal His6-tagged recombinant, human, full-length PRAK, for use in Kinase Assays.

    merck millipore,默克密理博,14-334M,PRAK Protein, active, 250 µg

  • 产品介绍
  • merck millipore,默克密理博,14-334M,PRAK Protein, active, 250 µg

    描述
    产品目录编号 14-334M
    品牌系列 Upstate
    商名
    • Upstate
    描述 PRAK Protein, active, 250 µg
    概述 N-terminal His6-tagged recombinant, human, full-length PRAK
    应用
    应用 Active, N-terminal His6-tagged recombinant, human, full-length PRAK, for use in Kinase Assays.
    主要应用
    • Kinase Assay
    生物信息
    来源 expressed by baculovirus in Sf21 insect cells
    品种 Human
    特异活性 For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.
    Entrez基因编号
    • NM_139078.1
    • NM_003668.2
    Entrez基因汇总 The protein encoded by this gene is a member of the serine/threonine kinase family. In response to cellular stress and proinflammatory cytokines, this kinase is activated through its phosphorylation by MAP kinases including MAPK1/ERK, MAPK14/p38-alpha, and MAPK11/p38-beta. In vitro, this kinase phosphorylates heat shock protein HSP27 at its physiologically relevant sites. Two alternately spliced transcript variants of this gene encoding distinct isoforms have been reported.
    基因符号
    • PRAK
    • MAPKAPK5
    蛋白靶 PRAK
    纯化方法 Ni2+/NTA-agarose
    靶子系列 CAMK
    UniProt编号
    • Q8IW41
    UniProt汇总 FUNCTION: SwissProt: Q8IW41 # Mediates stress-induced small heat shock protein 27 phosphorylation.
    SIZE: 473 amino acids; 54220 Da
    SUBUNIT: Interacts with SQSTM1.
    SUBCELLULAR LOCATION: Cytoplasm (Probable). Nucleus. Note=Also observed in the nucleus.
    TISSUE SPECIFICITY: Expressed ubiquitously.
    PTM: Phosphorylated on Thr-182; which is the regulatory phosphorylation site and is located on the T-loop/loop 12.
    SIMILARITY: SwissProt: Q8IW41 ## Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. & Contains 1 protein kinase domain.
    产品使用声明
    质量保证 routinely evaluated by phosphorylation of PRAK Substrate Peptide
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 6 months at -70C
    包装信息
    数量 250 µg
    包装 Also available in 15 μg size (cat#14-334) and in bulk (cat# 14-334-K).

    merck millipore,默克密理博,14-334M,PRAK Protein, active, 250 µg

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