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品种反应性 主要应用 宿主 格式 抗体类型 H IH(P) M Affinity Purified Monoclonal Antibody 描述 产品目录编号 05-1108 Replaces CBL71 描述 Anti-Insulin Antibody, clone1 背景信息 Insulin is a polypeptide hormone that regulates carbohydrate metabolism. Apart from being the primary agent in carbohydrate homeostasis, it has effects on fat metabolism. 产品信息 格式 Affinity Purified 控制 - Human pancreas tissue.
演示 The monoclonal is presented as 1mg in 1ml phosphate buffered saline containing 10mM sodium azide. We recommend that each laboratory determine an optimum working titre for use in its particular application. 应用 应用 Anti-Insulin Antibody, clone1 is an antibody against Insulin for use in IH(P). 主要应用 - Immunohistochemistry (Paraffin)
生物信息 免疫原品种 Biosynthetic human insulin 克隆 MAB1 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Mouse 特异性 This antibody recognizes an epitope including the amino acid B30. 同种型 IgG1 品种反应性 Human Species Reactivity Note Human 抗体类型 Monoclonal Antibody Entrez基因编号 - P01308
基因符号 - proinsulin
- ILPR
- IRDN
- OTTHUMP00000011161
- OTTHUMP00000011162
- OTTHUMP00000196038
- insulin
纯化方法 Affinity Purfied UniProt编号 - P01308
UniProt汇总 FUNCTION: Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.
SUBUNIT STRUCTURE: Heterodimer of a B chain and an A chain linked by two disulfide bonds.
SUBCELLULAR LOCATION: Secreted.
INVOLVEMENT IN DISEASE: Defects in INS are the cause of familial hyperproinsulinemia [MIM:176730].
PHARMACEUTICAL USE: Available under the names Humulin or Humalog (Eli Lilly) and Novolin (Novo Nordisk). Used in the treatment of diabetes. Humalog is an insulin analog with 52-Lys-Pro-53 instead of 52-Pro-Lys-53.
SEQUENCE SIMILARITIES: Belongs to the insulin family.
SEQUENCE CAUTION: The sequence AAA59179.1 differs from that shown. Reason: Erroneous gene model prediction.产品使用声明 质量保证 Evaluated by Immunohistochemistry in human pancreas tissue.
Immunohistochemistry Analysis: 1.25 µg/mL of this antibody detected insulin in human pancreas tissue.使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Store at 2-8°C and use within 1 year from date of receipt. 包装信息 数量 1 mg
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下一件merck millipore产品：merck millipore,默克密理博,MABC34,Anti-Beclin-1 Antibody, clone 9A1.1
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