merck millipore,默克密理愽
  • merck millipore,默克密理博,MAB1611,Anti-Keratin Epithelial Antibody, clone AE3

  • merck millipore,默克密理博,MAB1611,Anti-Keratin Epithelial Antibody, clone AE3

    产品名称：Anti-Keratin Epithelial Antibody, clone AE3
    产品型号：MAB1611
    Anti-Keratin Epithelial Antibody, clone AE3 is an antibody against Keratin Epithelial for use in WB, IH(P).

    merck millipore,默克密理博,MAB1611,Anti-Keratin Epithelial Antibody, clone AE3

  • 产品介绍
  • merck millipore,默克密理博,MAB1611,Anti-Keratin Epithelial Antibody, clone AE3

    重要规格表

    品种反应性 主要应用 宿主 格式 抗体类型
    Rb, B, Ch, H, M, Mk, RWBMPurifiedMonoclonal Antibody
    描述
    产品目录编号 MAB1611
    Replaces 04-588
    品牌系列 Chemicon®
    商名
    • Chemicon
    描述 Anti-Keratin Epithelial Antibody, clone AE3
    Alternate Names
    • Type II Cytokeratin
    产品信息
    格式 Purified
    控制
    • POSITIVE CONTROL: MCF-7, RT112, and A431 cell lines.
    演示 Liquid in PBS. Contains 0.1% sodium azide.
    应用
    应用 Anti-Keratin Epithelial Antibody, clone AE3 is an antibody against Keratin Epithelial for use in WB, IH(P).
    主要应用
    • Western Blotting
    应用说明 Immunohistochemistry on unfixed frozen sections or formalin-fixed paraffin-embedded tissue sections. For paraffin-embedded sections, antigen retrieval (HEIR or trypsin treatment) is strongly recommended.

    Western blotting: Clone AE3 recognizes the 65 to 67, 64, 59, 58, 56 and 52 kDa human cytokeratins of the basic subfamily.

    Optimal working dilutions must be determined by end user.
    生物信息
    免疫原品种 Human epidermal cells
    克隆 AE3
    浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration.
    宿主 Mouse
    特异性 Recognizes most of the basic (Type II) keratins, HMW cytokeratins. It is broadly reactive and stains positively almost all epithelia and their neoplasms. AE3 reacts with all layers of epidermis (basal layer and above). The antibody is an excellent marker for distinguishing carcinomas from non-epithelial tumours. It has been used for studying the immunolocalisation of epidermal keratins, tissue distribution of keratins, various diseases of epidermis, oral mucosa and other epithelia and other epithelia development. AE3 and AE1 (Catalog Number MAB1612) have been used extensively for distinguishing carcinoma from non-carcinoma.
    同种型 IgG1
    品种反应性 RabbitBovineChickenHumanMouseMonkeyRat
    抗体类型 Monoclonal Antibody
    Entrez基因编号
    • NM_002273.2
    基因符号
    • CARD2
    • KRT8
    • KO
    • K8
    • CYK8
    • Keratin-8
    • CK-8
    • Cytokeratin-8
    • K2C8
    • CK8
    UniProt编号
    • P05787
    UniProt汇总 FUNCTION: SwissProt: P05787 # Together with KRT19, helps to link the contractile apparatus to dystrophin at the costameres of striated muscle.
    SIZE: 483 amino acids; 53704 Da
    SUBUNIT: Heterotetramer of two type I and two type II keratins. keratin-8 associates with keratin-18. Associates with KRT20. Interacts with HCV core protein and PNN. When associated with KRT19, interacts with DMD. Interacts with TCHP.
    SUBCELLULAR LOCATION: Cytoplasm.
    TISSUE SPECIFICITY: Observed in muscle fibers accumulating in the costameres of myoplasm at the sarcolemma membrane in structures that contain dystrophin and spectrin. Expressed in gingival mucosa and hard palate of the oral cavity.
    PTM: Phosphorylation on serine residues is enhanced during EGF stimulation and mitosis. Ser-74 phosphorylation plays an important role in keratin filament reorganization.
    DISEASE:SwissProt: P05787 # Defects in KRT8 are a cause of cryptogenic cirrhosis [MIM:215600].
    SIMILARITY: SwissProt: P05787 ## Belongs to the intermediate filament family.
    MISCELLANEOUS: There are two types of cytoskeletal and microfibrillar keratin: I (acidic; 40-55 kDa) and II (neutral to basic; 56-70 kDa).
    产品使用声明
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 Maintain at 2-8°C in undiluted aliquots for up to 6 months from date of receipt.
    包装信息
    数量 500 µg

    merck millipore,默克密理博,MAB1611,Anti-Keratin Epithelial Antibody, clone AE3

上一件merck millipore产品：merck millipore,默克密理博,ABS467,Anti-MAGI Antibody1
下一件merck millipore产品：merck millipore,默克密理博,ABC242,Anti-CRKL Antibody


相关产品

merck millipore,默克密理博,17-494,PIP3 Quantification TR-FRET Assay merck millipore,默克密理博,17-494,PIP3 Quantification TR-FRET Assay

merck millipore,默克密理博,SF-1019,FABP3; Human, Cyanine 5 RNA Detection Probe,SmartFlare merck millipore,默克密理博,SF-1019,FABP3; Human, Cyanine 5 RNA Detection Probe,SmartFlare

merck millipore,默克密理博,MAB994,Anti-Reovirus Type 3 Antibody, σ 1 hemagglutinin, clone 9BG5 merck millipore,默克密理博,MAB994,Anti-Reovirus Type 3 Antibody, σ 1 hemagglutinin, clone 9BG5

merck millipore,默克密理博,12-243,S6 Kinase/Rsk2 Substrate Peptide 2 merck millipore,默克密理博,12-243,S6 Kinase/Rsk2 Substrate Peptide 2

merck millipore,默克密理博,ABS467,Anti-MAGI Antibody1 merck millipore,默克密理博,ABS467,Anti-MAGI Antibody1

merck millipore,默克密理博,ABC242,Anti-CRKL Antibody merck millipore,默克密理博,ABC242,Anti-CRKL Antibody

merck millipore,默克密理博,EZMADP-60K,Mouse Adiponectin ELISA merck millipore,默克密理博,EZMADP-60K,Mouse Adiponectin ELISA

merck millipore,默克密理博,SLGL0250S,Millex-GS，0.22 µm，混合纤维素酯，25 mm，25 mm，带 Luer 出口，环氧乙烷灭菌 merck millipore,默克密理博,SLGL0250S,Millex-GS，0.22 µm，混合纤维素酯，25 mm，25 mm，带 Luer 出口，环氧乙烷灭菌

merck millipore,默克密理博,MAB5354,Anti-Amyloid β Precursor Protein Antibody, KPI domain, clone 4.1 merck millipore,默克密理博,MAB5354,Anti-Amyloid β Precursor Protein Antibody, KPI domain, clone 4.1

merck millipore,默克密理博,07-689,Anti-EZH2 Antibody merck millipore,默克密理博,07-689,Anti-EZH2 Antibody


whatman,沃特曼,nalgene,耐洁,merck millipore,默克密理愽,sartorius,赛多利斯,pall,颇尔
thermo fisher,赛默飞世尔,GE,MN,macherey-nagel,advantec,wheaton,brand,普兰德,welch,airtech


上海羽令过滤器材有限公司版权所有 Copyright ©  www.yl-guolv.com  Powered by 羽令集团—信息技术部