merck millipore,默克密理博,ABS467,Anti-MAGI Antibody1

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merck millipore,默克密理博,ABS467,Anti-MAGI Antibody1
产品名称：Anti-MAGI Antibody1
产品型号：ABS467
Detect MAGI using this rabbit polyclonal antibody, Anti-MAGI Antibody1 validated for use in western blotting.

merck millipore,默克密理博,ABS467,Anti-MAGI Antibody1

产品介绍

merck millipore,默克密理博,ABS467,Anti-MAGI Antibody1

重要规格表

品种反应性	主要应用	宿主	格式	抗体类型
M	WB	Rb	Affinity Purified	Polyclonal Antibody

描述
产品目录编号	ABS467
描述	Anti-MAGI Antibody1
Alternate Names	MAGI1 Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 Atrophin-1-interacting protein 3 AIP-3 BAI1-associated protein 1 BAP-1 Membrane-associated guanylate kinase inverted 1 MAGI-1 Trinucleotide repeat-containing gene 19 protein
背景信息	The protein named Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1, Atrophin-1-interacting protein 3m(AIP-3), BAI1-associated protein 1 (BAP-1), Membrane-associated guanylate kinase inverted 1 (MAGI-1), Trinucleotide repeat-containing gene 19 protein, or WW domain-containing protein 3 (WWP3) and encoded by the human gene named MAGI1/AIP3/BAIAP1/BAP1/TNRC19 is cell junction scaffolding protein that regulates acid-induced ASIC3 currents by modulating the expression of ASIC3 at the cell surface. MAGI1 has many isoforms that are differentially expressed in various tissues at the epithelial cell boundaries. MAGI1 is widely expressed with the exception of skeletal muscle. Isoform 1, isoform 2 and isoform 6 are highly expressed in colon, kidney, lung, liver, and pancreas. Isoform 5 is predominantly expressed in brain and heart. Isoform 3 and isoform 4 are highly expressed in pancreas and brain. Interestingly MAGI1 has also been recently identified as a tumor suppressor protein through its inhibitory action upon the Wnt/beta-catenin signaling pathway in experimental colon cancer cells. We offer a rabbit polyclonal Anti-MAGI1 Antibody that has been validated in western blot on mouse kidney tissue lysates.

产品信息
格式	Affinity Purified
演示	Purified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide and 50% glycerol.

应用
应用	Detect MAGI using this rabbit polyclonal antibody, Anti-MAGI Antibody1 validated for use in western blotting.
主要应用	Western Blotting

生物信息
免疫原品种	KLH-conjugated linear peptide corresponding to human MAGI1.
浓缩	Please refer to the Certificate of Analysis for the lot-specific concentration.
宿主	Rabbit
特异性	This antibody can recognize all isoforms of MAGI1.
品种反应性	Mouse
抗体类型	Polyclonal Antibody
基因符号	TNRC19 MAGI1 AIP3 BAIAP1 BAP1
纯化方法	Antigen Affinity purified
UniProt编号	Q96QZ7

产品使用声明
质量保证	Evaluated by Western Blotting in mouse kidney tissue lysate. Western Blotting Analysis: A 1:500 dilution of this antibody detected MAGI1 in mouse kidney tissue lysate.
使用声明	Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

储存和货运信息
存储条件	Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance. Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage.

储存和货运信息

存储条件

Stable for 1 year at -20°C from date of receipt.
Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage.