merck millipore,默克密理博,MAB1576,Anti-Muscarinic Acetylcholine Receptor m4 Antibody, clone 17F10.2

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Merck Millipore 默克密理愽

品种反应性	主要应用	宿主	格式	抗体类型
R, M, Mk	WB, ICC	M	Ascites	Monoclonal Antibody

描述
产品目录编号	MAB1576
品牌系列	Chemicon®
商名	Chemicon
描述	Anti-Muscarinic Acetylcholine Receptor m4 Antibody, clone 17F10.2

产品信息
格式	Ascites
演示	Liquid in 0.02M Phosphate buffer, 0.25 M NaCl, pH=7.6 with 0.1% sodium azide.

应用
应用	This Anti-Muscarinic Acetylcholine Receptor m4 Antibody, clone 17F10.2 is validated for use in IC, IP, WB for the detection of Muscarinic Acetylcholine Receptor m4.
主要应用	Western Blotting Immunocytochemistry
应用说明	Immunohistochemistry (rat and monkey) Western blot (rat, mouse, human): ECL 4-10 μg/mL Immunoprecipitation (rat) Optimal working dilutions must be determined by the end user.

生物信息
免疫原品种	m4 receptor i3 loop (human), fused to GST
克隆	17F10.2
浓缩	Please refer to the Certificate of Analysis for the lot-specific concentration.
宿主	Mouse
特异性	m4 muscarinic acetylcholine receptor. No reactivity with the other subtypes.
同种型	IgG1
品种反应性	RatMouseMonkey
抗体类型	Monoclonal Antibody
Entrez基因编号	NM_000741.2
Entrez基因汇总	The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The clinical implications of this receptor are unknown; however, mouse studies link its function to adenylyl cyclase inhibition.
基因符号	HM4 CHRM4
UniProt编号	P08173
UniProt汇总	FUNCTION: SwissProt: P08173 # The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is inhibition of adenylate cyclase. SIZE: 479 amino acids; 53049 Da SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein. SIMILARITY: SwissProt: P08173 ## Belongs to the G-protein coupled receptor 1 family.

产品使用声明
使用声明	Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

储存和货运信息
存储条件	Maintain at 2-8°C in undiluted aliquots for up to 6 months.

包装信息
数量	100 µL

merck millipore,默克密理博,MAB1576,Anti-Muscarinic Acetylcholine Receptor m4 Antibody, clone 17F10.2

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