merck millipore,默克密理愽
  • merck millipore,默克密理博,MAB1397Z,Anti-ICAM-1 Antibody, clone 3E2B, Azide Free

  • merck millipore,默克密理博,MAB1397Z,Anti-ICAM-1 Antibody, clone 3E2B, Azide Free

    产品名称：Anti-ICAM-1 Antibody, clone 3E2B, Azide Free
    产品型号：MAB1397Z
    Anti-ICAM-1 Antibody, clone 3E2B, Azide Free detects level of ICAM-1 & has been published & validated for use in ELISA, FC, FUNC, IC, IH.

    merck millipore,默克密理博,MAB1397Z,Anti-ICAM-1 Antibody, clone 3E2B, Azide Free

  • 产品介绍
  • merck millipore,默克密理博,MAB1397Z,Anti-ICAM-1 Antibody, clone 3E2B, Azide Free

    重要规格表

    品种反应性 主要应用 宿主 格式 抗体类型
    MIHC, ELISA, FC, ICCAHmPurifiedMonoclonal Antibody
    描述
    产品目录编号 MAB1397Z
    Replaces CBL1331F
    品牌系列 Chemicon®
    商名
    • Chemicon
    描述 Anti-ICAM-1 Antibody, clone 3E2B, Azide Free
    Alternate Names
    • MAB1397
    • CD54
    产品信息
    格式 Purified
    演示 Purified IgG prepared by affinity chromatography on Protein G agarose beads. Liquid at 1 mg/mL in sterile-filtered PBS, containing no preservatives. Endotoxin level 4.13EU/mg
    应用
    应用 Anti-ICAM-1 Antibody, clone 3E2B, Azide Free detects level of ICAM-1 & has been published & validated for use in ELISA, FC, FUNC, IC, IH.
    主要应用
    • Immunohistochemistry
    • ELISA
    • Flow Cytometry
    • Immunocytochemistry
    应用说明 Immunocytochemistry: Live or acetone fixed cells

    ELISA

    Immunohistochemistry of acetone fixed frozen sections. (Paraffin not tested).

    Flow Cytometry: Suggested working dilution 50 μg/mL. Use 5 mL of this dilution to label 0.5 x 10(e6) cells.

    Immunoprecipitation: use protein G or rabbit anti-hamster IgG secondary

    Clone 3E2B is reported to be function blocking against murine ICAM-1.

    Optimal working dilutions must be determined by end user.
    生物信息
    克隆 3E2B
    宿主 Armenian Hamster
    特异性 MAB1371Z is reactive with mouse ICAM-1 (CD54), which is present on T-cells, B-cells, monocytes and endothelial cells, epithelial cells, dendritic cells and keratinocytes. Expression of CD54 is increased after stimulation with cytokines and LPS, and it also plays a role in B cell-T cell interactions.
    同种型 IgG
    品种反应性 Mouse
    抗体类型 Monoclonal Antibody
    Entrez基因编号
    • NM_000201.1
    Entrez基因汇总 ICAM1 (CD54) is typically expressed on endothelial cells and cells of the immune system. ICAM1 binds to integrins of type CD11a / CD18, or CD11b / CD18. ICAM1 is also exploited by Rhinovirus as a receptor.
    基因符号
    • ICAM-1
    • ICAM1
    • P3.58
    • BB2
    • CD54
    UniProt编号
    • P05362
    UniProt汇总 FUNCTION: SwissProt: P05362 # ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). In case of rhinovirus infection acts as a cellular receptor for the virus. Also acts as receptor for some coxsackieviruses.
    SIZE: 532 amino acids; 57825 Da
    SUBUNIT: Interacts with human herpesvirus 8 MIR2 protein (Probable).
    SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane protein.
    PTM: Monoubiquitinated, which is promoted by MARCH9 and leads to endocytosis.
    SIMILARITY: SwissProt: P05362 ## Belongs to the immunoglobulin superfamily. ICAM family. & Contains 5 Ig-like C2-type (immunoglobulin-like) domains.
    产品使用声明
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 Maintain frozen at -20°C in undiluted aliquots for up to 12 months. Avoid repeated freeze-thaw cycles.
    包装信息
    数量 100 µg

    merck millipore,默克密理博,MAB1397Z,Anti-ICAM-1 Antibody, clone 3E2B, Azide Free

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