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经验配方 CAS号 C₁₇H₃₁F₃O 141022-99-3 描述 概述 A novel Ca2+-independent and reversible inhibitor of phospholipase A2 (PLA2; IC50 = 3.8 µM). May also inhibit Ca2+-dependent PLA2 at much higher concentrations (IC50 = 45 µM). 产品目录编号 506274 品牌系列 Calbiochem®
同义词 Palmitoyl Trifluoromethyl Ketone 参考 参考 Conde-Frieboes, K., et al. 1996. J. Am. Chem. Soc. 118, 5519.
Lio, Y.C., et al. 1996. Biochim. Biophys. Acta 1302, 55.
Ackermann, E.J., et al. 1995. J. Biol. Chem. 270, 445.产品信息 CAS号 141022-99-3 具有ATP竞争性 N 形式 Liquid 配方 In ethanol. Hill配方 C₁₇H₃₁F₃O 化学配方 C₁₇H₃₁F₃O Molar Mass 308.4 可逆 Y 结构配方图像 生物信息 主靶 PLA₂ 主靶IC50 3.8 µM and 45 µM against phospholipase A2 (PLA2) and Ca2+-dependent PLA2, respectively. 纯度 ≥97% by TLC 理化信息 细胞可渗透 N 溶解度 DMSO or EtOH 储存和货运信息 货运代码 Shipped with Blue Ice or with Dry Ice
毒性 Standard Handling
储存 -20°C
无需冷冻 No
特殊指南 Following reconstitution in DMSO, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C. Product has a very low melting point. The product will change from a solid to a liquid if held in your hand or kept at room temperature or warmer for any period of time. It is best to keep the product cool while in use by placing it in the refrigerator or on ice during experimentation. Once diluted in buffer, do not store in aqueous solutions for >1 day.
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