merck millipore,默克密理愽
  • merck millipore,默克密理博,MAB1160,Anti-gC1q-R/p33 Antibody, CT, aa 204-218, clone 74.5.2

  • merck millipore,默克密理博,MAB1160,Anti-gC1q-R/p33 Antibody, CT, aa 204-218, clone 74.5.2

    产品名称：Anti-gC1q-R/p33 Antibody, CT, aa 204-218, clone 74.5.2
    产品型号：MAB1160
    This Anti-gC1q-R/p33 Antibody, C-terminus, aa 204-218, clone 74.5.2 is validated for use in ELISA, FC, IP, WB for the detection of gC1q-R/p33.

    merck millipore,默克密理博,MAB1160,Anti-gC1q-R/p33 Antibody, CT, aa 204-218, clone 74.5.2

  • 产品介绍
  • merck millipore,默克密理博,MAB1160,Anti-gC1q-R/p33 Antibody, CT, aa 204-218, clone 74.5.2

    重要规格表

    品种反应性 主要应用 宿主 格式 抗体类型
    M, HWB, ELISA, FCMPurifiedMonoclonal Antibody
    描述
    产品目录编号 MAB1160
    品牌系列 Chemicon®
    商名
    • Chemicon
    描述 Anti-gC1q-R/p33 Antibody, CT, aa 204-218, clone 74.5.2
    Alternate Names
    • Glycoprotein gC1qBP
    • C1q-R
    • C1q Receptor
    产品信息
    格式 Purified
    演示 Purified immunoglobulin. Liquid in 0.02M PBS pH 7.6, 0.25M NaCl with 0.1% sodium azide.
    应用
    应用 This Anti-gC1q-R/p33 Antibody, C-terminus, aa 204-218, clone 74.5.2 is validated for use in ELISA, FC, IP, WB for the detection of gC1q-R/p33.
    主要应用
    • Western Blotting
    • ELISA
    • Flow Cytometry
    应用说明 Western blot

    Immunoprecipitation

    ELISA

    FACS

    Optimal working dilutions must be determined by end user.
    生物信息
    免疫原品种 Recombinant human gC1q-R.
    表位 C-terminus, aa 204-218
    克隆 74.5.2
    浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration.
    宿主 Mouse
    特异性 Recognizes the mature form and truncated forms of gC1q-R/p33 complement receptor. Antibody is directed against the carboxyl-terminus of the receptor (residues 204-218), a portion of the molecule specifies interaction with HK and Factor XII and blocks binding of HK to gC1q-R.
    同种型 IgG1κ
    品种反应性 MouseHuman
    抗体类型 Monoclonal Antibody
    Entrez基因编号
    • NM_012072.3
    Entrez基因汇总 The protein encoded by this gene is a cell-surface glycoprotein and type I membrane protein that was originally identified as a myeloid cell-specific marker. The encoded protein was once thought to be a receptor for C1q, but now is thought to instead be involved in intercellular adhesion and in the clearance of apoptotic cells. The intracellular cytoplasmic tail of this protein has been found to interact with moesin, a protein known to play a role in linking transmembrane proteins to the cytoskeleton and in the remodelling of the cytoskeleton.
    基因符号
    • C1qRP
    • CD93
    • MXRA4
    • C1qRp
    • C1qR(P)
    • C1qR
    • dJ737E23.1
    • C1QR1
    • CDw93
    • p
    UniProt编号
    • Q9NPY3
    UniProt汇总 FUNCTION: SwissProt: Q9NPY3 # Receptor (or element of a larger receptor complex) for C1q, mannose-binding lectin (MBL2) and pulmonary surfactant protein A (SPA). May mediate the enhancement of phagocytosis in monocytes and macrophages upon interaction with soluble defense collagens. May play a role in intercellular adhesion.
    SIZE: 652 amino acids; 68560 Da
    SUBUNIT: Interacts with HCV core protein.
    SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane protein.
    TISSUE SPECIFICITY: Highly expressed in endothelial cells, platelets, cells of myeloid origin, such as monocytes and neutrophils. Not expressed in cells of lymphoid origin.
    PTM: N- and O-glycosylated.
    SIMILARITY: SwissProt: Q9NPY3 ## Contains 1 C-type lectin domain. & Contains 5 EGF-like domains.
    产品使用声明
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 Maintain refrigerated at 2-8°C in undiluted aliquots for up to 12 months.
    包装信息
    数量 100 µg

    merck millipore,默克密理博,MAB1160,Anti-gC1q-R/p33 Antibody, CT, aa 204-218, clone 74.5.2

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