merck millipore,默克密理博,MAB11041,Anti-Serotonin receptor 1A Antibody, clone 19A9.2

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Merck Millipore 默克密理愽

品种反应性	主要应用	宿主	格式	抗体类型
H, R	IHC, WB	M	Purified	Monoclonal Antibody

描述
产品目录编号	MAB11041
描述	Anti-Serotonin receptor 1A Antibody, clone 19A9.2
Alternate Names	5-HT1a receptor 5-hydroxytryptamine (serotonin) receptor 1A 5-hydroxytryptamine receptor 1A guanine nucleotide-binding regulatory protein-coupled receptor Serotonin receptor 1A G protein coupled receptor
背景信息	Serotonin receptor 1A, also known as 5-hydroxytryptamine receptor 1A, is a member of the G protein-coupled receptor family. Serotonin receptor 1A has been found to be expressed highly in the septum and hippocampus. Serotonin receptor 1A seems to have an inhibitory effect on Ca2+ channels, via N-channels and L-channels. The receptor actuates voltage-sensitive slowing using the N-channels and actuates steady state inhibition using the L-channels.

产品信息
格式	Purified
控制	Rat brain tissue lysate
演示	Purified mouse monoclonal IgMκ in buffer containing PBS with 0.05% sodium azide.

应用
应用	Anti-Serotonin receptor 1A Antibody, clone 19A9.2 is an antibody against Serotonin receptor 1A for use in WB, IH.
主要应用	Immunohistochemistry Western Blotting
应用说明	Immunohistochemistry Analysis: 1:400 dilution from a previous lot detected Serotonin receptor 1A in normal human brain tissue.

生物信息
免疫原品种	KLH-conjugated linear peptide corresponding to rat Serotonin receptor 1A.
克隆	19A9.2
浓缩	Please refer to the Certificate of Analysis for the lot-specific concentration.
宿主	Mouse
特异性	0
同种型	IgMκ
品种反应性	HumanRat
Species Reactivity Note	Demonstrated to react with rat and human.
抗体类型	Monoclonal Antibody
Entrez基因编号	NP_036717
Entrez基因汇总	Regulates AMPA receptor channels in the prefrontal cortex; regulation is mediated via inhibition of Ca2+/calmodulin-dependent kinase II [RGD].
基因符号	G-21 HTR1A 5-HT1A 5HT1a ADRB2RL 5-HT-1A ADRBRL
纯化方法	Ion Exchange
UniProt编号	P19327
UniProt汇总	FUNCTION: This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity. SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein. SEQUENCE SIMILARITIES: Belongs to the G-protein coupled receptor 1 family. 5-hydroxytryptamine receptor subfamily. HTR1A sub-subfamily.

产品使用声明
质量保证	Evaluated by Western Blot in rat brain tissue lysate. Western Blot Analysis: 0.5 µg/mL of this antibody detected Serotonin receptor 1A on 10 µg of rat brain tissue lysate.
使用声明	Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

储存和货运信息
存储条件	Stable for 1 year at 2-8°C from date of receipt.

包装信息
数量	100 µg

merck millipore,默克密理博,MAB11041,Anti-Serotonin receptor 1A Antibody, clone 19A9.2

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