• merck millipore,默克密理博,ABS460,Anti-LEMD3 Antibody
  • merck millipore,默克密理博,ABS460,Anti-LEMD3 Antibody

    产品名称:Anti-LEMD3 Antibody
    产品型号:ABS460
    Anti-LEMD3 Antibody is a highly specific rabbit polyclonal antibody, that targets LEM domain-containing protein 3 & has been tested in western blotting & IHC.

    merck millipore,默克密理博,ABS460,Anti-LEMD3 Antibody

  • 产品介绍
  • merck millipore,默克密理博,ABS460,Anti-LEMD3 Antibody

    重要规格表

    品种反应性 主要应用 宿主 格式 抗体类型
    HIHC, WBRbAffinity PurifiedPolyclonal Antibody
    描述
    产品目录编号 ABS460
    描述 Anti-LEMD3 Antibody
    Alternate Names
    • Inner nuclear membrane protein Man1
    • LEM domain containing 3
    背景信息 LEM domain-containing protein 3 (LEMD3), also known as Inner nuclear membrane protein Man1 (MAN1), is an inner nuclear membrane protein that interacts with BMP and activin-TGF-beta receptor-activated Smads and antagonizes TGF-beta signaling in human cells. Additionally, LEMD3 is shown to Interact with SMAD1, SMAD2, SMAD3 and SMAD5. Studies also show that LEMD3 binds to both the phosphorylated and the unphosphorylated R-SMADS. LEMD3 is expressed in heart, brain, placenta, lung, liver and skeletal muscle. Defects in LEMD3 are shown to cause disorders, such as osteopoikilosis, Buschke-Ollendorff syndrome (BOS), and melorheostosis (MEL).
    产品信息
    格式 Affinity Purified
    控制
    • Human colon tissue lysate
    演示 Purified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide.
    应用
    应用 Anti-LEMD3 Antibody is a highly specific rabbit polyclonal antibody, that targets LEM domain-containing protein 3 & has been tested in western blotting & IHC.
    主要应用
    • Immunohistochemistry
    • Western Blotting
    应用说明 Immunohistochemistry Analysis: 2.5 µg/mL from a representative lot detected LEMD3 in human colon tissue.
    生物信息
    免疫原品种 KLH-conjugated linear peptide corresponding to human LEMD3.
    浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration.
    宿主 Rabbit
    品种反应性 Human
    抗体类型 Polyclonal Antibody
    基因符号
    • MAN1
    • LEMD3
    纯化方法 Antigen Affinity purified
    UniProt编号
    • Q9Y2U8
    产品使用声明
    质量保证 Evaluated by Western Blotting in human colon tissue lysate.

    Western Blotting Analysis: 1 µg/mL of this antibody detected LEMD3 in 15 µg of human colon tissue lysate.
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 Stable for 1 year at 2-8°C from date of receipt.
    包装信息
    数量 100 µg

    merck millipore,默克密理博,ABS460,Anti-LEMD3 Antibody

上一件merck millipore产品:merck millipore,默克密理博,14-548,MSK1 Protein, active, 10 µg
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