merck millipore,默克密理愽
  • merck millipore,默克密理博,IL031,Interleukin-2 Protein, Recombinant mouse

  • merck millipore,默克密理博,IL031,Interleukin-2 Protein, Recombinant mouse

    产品名称：Interleukin-2 Protein, Recombinant mouse
    产品型号：IL031
    The recombinant nouse Interleukin-2 protein (or IL-2 protein) is a potent lymphoid cell growth factor which exerts its biological activity primarily on T cells.

    merck millipore,默克密理博,IL031,Interleukin-2 Protein, Recombinant mouse

  • 产品介绍
  • merck millipore,默克密理博,IL031,Interleukin-2 Protein, Recombinant mouse

    重要规格表

    主要应用 品种 纯度
    CULTMouseGreater than 97% by SDS-PAGE and HPLC analysis.
    描述
    产品目录编号 IL031
    品牌系列 Chemicon®
    商名
    • Chemicon
    描述 Interleukin-2 Protein, Recombinant mouse
    概述 Interleukin-2 (IL-2) is a potent lymphoid cell growth factor which exerts its biological activity primarily on T cells. IL031 is a 17.2 kDa protein containing 149 amino acid residues.
    Alternate Names
    • IL-2
    产品信息
    演示 Lyophilized powder from 10 mM NaCitrate 4.0 pH.
    应用
    应用 The recombinant nouse Interleukin-2 protein (or IL-2 protein) is a potent lymphoid cell growth factor which exerts its biological activity primarily on T cells.
    主要应用
    • Cell Culture
    应用说明 For most in vitro applications, IL-2 exerts its biological activity in the concentration range of 0.1 to 1.0 ng/mL.
    生物信息
    纯度 Greater than 97% by SDS-PAGE and HPLC analysis.
    品种 Mouse
    特异活性 Chemicon's mouse IL-2 is fully biologically active when compared to standards. The ED(50) as determined by the dose-dependent stimulation of mouse CTLL-2 cells is <br /><br /><= 0.2 ng/mL, corresponding to a specific activity of >= 5 x 10(E6) units /mg.
    Entrez基因汇总 The protein encoded by this gene is a secreted cytokine that is important for the proliferation of T and B lymphocytes. The receptor of this cytokine is a heterotrimeric protein complex whose gamma chain is also shared by interleukin 4 (IL4) and interleukin 7 (IL7). The expression of this gene in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. The targeted disruption of a similar gene in mice leads to ulcerative colitis-like disease, which suggests an essential role of this gene in the immune response to antigenic stimuli.
    UniProt编号
    • P04351
    • P60568
    UniProt汇总 FUNCTION: SwissProt: P60568 # Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Can stimulate B-cells, monocytes, lymphokine- activated killer cells, natural killer cells, and glioma cells.
    SIZE: 153 amino acids; 17628 Da
    SUBCELLULAR LOCATION: Secreted.
    DISEASE:SwissProt: P60568 # A chromosomal aberration involving IL2 is found in a form of T-cell acute lymphoblastic leukemia (T-ALL). Translocation t(4;16)(q26;p13) with involves TNFRSF17.
    SIMILARITY: SwissProt: P60568 ## Belongs to the IL-2 family.
    产品使用声明
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 The lyophilized IL-2, though stable at room temperature, is best stored desiccated at -20°C. After a quick spin, reconstitute with sterile water to a concentration of 0.1-1.0 mg/mL. This solution can be diluted into other buffered solutions or stored frozen for future use. Reconstituted IL-2 should be stored in working aliquots at -20°C for up to 6 months.
    包装信息
    数量 20 µg

    merck millipore,默克密理博,IL031,Interleukin-2 Protein, Recombinant mouse

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