merck millipore,默克密理博,IL012,Interleukin-13 Protein, Recombinant human

搜索"Merck Millipore 密理愽"产品

Merck Millipore 默克密理愽

当前位置：首页 > >Merck Millipore > 生命科学研究
生命科学研究

merck millipore,默克密理博,IL012,Interleukin-13 Protein, Recombinant human
产品名称：Interleukin-13 Protein, Recombinant human
产品型号：IL012
The recombinant human Interleukin-13 protein (or IL-13 protein) is a immunoregulatory protein produced by activated T-lymphocytes.

merck millipore,默克密理博,IL012,Interleukin-13 Protein, Recombinant human

产品介绍

merck millipore,默克密理博,IL012,Interleukin-13 Protein, Recombinant human

重要规格表

主要应用	品种	来源	纯度
CULT	Human	Human	Greater than 98% by SDS-PAGE and HPLC analysis. Endotoxin level is less than 0.1 ng per μg (1EU/μg) of IL-13.

描述
产品目录编号	IL012
品牌系列	Chemicon®
商名	Chemicon
描述	Interleukin-13 Protein, Recombinant human
概述	Interleukin-13 (IL-13) is a immunoregulatory protein produced by activated T-lymphocytes. The biological activities of IL-13 include the stimulation of B-cell proliferation and immunoglobulin production and induction of differentiation of B-cells and cells of monocytic lineage. Human IL-13 is a 12.5 kDa protein containing 114 amino acid residues.
Alternate Names	IL-13

产品信息
演示	The sterile filtered solution was lyophilized from 20 mM Sodium Phosphate, pH 7.0.

应用
应用	The recombinant human Interleukin-13 protein (or IL-13 protein) is a immunoregulatory protein produced by activated T-lymphocytes.
主要应用	Cell Culture
应用说明	For most in vitro applications, IL-13 exerts its biological activity in the concentration range of 0.1 to 10.0 ng/mL. Responding cells are (partial list): B-cells, monocytes.

生物信息
纯度	Greater than 98% by SDS-PAGE and HPLC analysis. Endotoxin level is less than 0.1 ng per μg (1EU/μg) of IL-13.
来源	Human
品种	Human
特异活性	The ED(50) as determined by the dose-dependent proliferation of TF-1 cells was <= 1.0 ng/mL, corresponding to a specific activity of >= 1 x 10(E6) units/mg.
Entrez基因编号	NM_002188.2
Entrez基因汇总	This gene encodes an immunoregulatory cytokine produced primarily by activated Th2 cells. This cytokine is involved in several stages of B-cell maturation and differentiation. It up-regulates CD23 and MHC class II expression, and promotes IgE isotype switching of B cells. This cytokine down-regulates macrophage activity, thereby inhibits the production of pro-inflammatory cytokines and chemokines. This cytokine is found to be critical to the pathogenesis of allergen-induced asthma but operates through mechanisms independent of IgE and eosinophils. This gene, IL3, IL5, IL4, and CSF2 form a cytokine gene cluster on chromosome 5q, with this gene particularly close to IL4.
基因符号	MGC116786 IL13 P600 NC30 IL-13 MGC116789 BHR1 ALRH MGC116788
UniProt编号	P35225
UniProt汇总	FUNCTION: SwissProt: P35225 # Cytokine. Inhibits inflammatory cytokine production. Synergizes with IL2 in regulating interferon-gamma synthesis. May be critical in regulating inflammatory and immune responses. SIZE: 132 amino acids; 14319 Da SUBCELLULAR LOCATION: Secreted. SIMILARITY: SwissProt: P35225 ## Belongs to the IL-4/IL-13 family.

产品使用声明
使用声明	Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

储存和货运信息
存储条件	The lyophilized powder is stable for a few weeks at room temperature, but best stored at -20°C. After a quick spin, reconstitutein water to a concentration of 0.1-1.0 mg/mL. Note: Slow to dissolve. This solution can be diluted into other buffered solutions and stored at 4ºC for 1 week or -20ºC for future use. Reconstituted human IL-13 should be stored in undiluted aliquots at -20°C for up to six months. Avoid repeated freeze/thaw cycles.

储存和货运信息

存储条件

The lyophilized powder is stable for a few weeks at room temperature, but best stored at -20°C. After a quick spin, reconstitutein water to a concentration of 0.1-1.0 mg/mL. Note: Slow to dissolve. This solution can be diluted into other buffered solutions and stored at 4ºC for 1 week or -20ºC for future use. Reconstituted human IL-13 should be stored in undiluted aliquots at -20°C for up to six months. Avoid repeated freeze/thaw cycles.