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品种反应性 主要应用 宿主 格式 抗体类型 R, M, H ICC, WB Rb Affinity Purified Polyclonal Antibody 描述 产品目录编号 ABN51 描述 Anti-Fox-3 Antibody Alternate Names - Fox-1 homolog C
- RNA binding protein fox-1 homolog 3
背景信息 Fox-3, also called hexaribonucleotide-binding protein 3, is a Fox-1 splicing protein that binds to RNA and controls alternative pre-mRNA splicing. Fox-3 seems to interact with PSF, activating neural cell-specific alternative splicing of the N30 exon of NMHC II-B. It is almost exclusively located in the neuronal nuclear matrix and may be used as a marker for nuclear speckles. 产品信息 格式 Affinity Purified 控制 - Mouse e16 brain tissue lysate
演示 Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. 应用 应用 Anti-Fox-3 Antibody detects level of Fox-3 & has been published & validated for use in WB, IH(P) & IC. 主要应用 - Immunocytochemistry
- Western Blotting
应用说明 Immunohistochemistry Analysis: 1:1,000 dilution from a representative lot detected Fox-3 in normal mouse frontal lobe and normal mouse cerebellum tissues.
Immunocytochemistry Analysis: 1:500 dilution from a representative lot detected Fox-3 in rat E18 Cortex/Hippo primary cultures.生物信息 免疫原品种 GST-tagged recombinant protein corresponding to the N-terminus of mouse Fox-3. 表位 N-terminus 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Rabbit 特异性 This antibody recognizes Fox-3 at the N-terminus. 品种反应性 RatMouseHuman Species Reactivity Note Demonstrated to react with Mouse, Human, and Rat. 抗体类型 Polyclonal Antibody Entrez基因编号 - NP_001034256
基因符号 - Rbfox3
纯化方法 Affinity purified UniProt编号 - Q8BIF2
UniProt汇总 FUNCTION: RNA-binding protein that regulates alternative splicing events (By similarity).
SUBCELLULAR LOCATION: Nucleus (By similarity). Cytoplasm (By similarity).
SEQUENCE SIMILARITIES: Contains 1 RRM (RNA recognition motif) domain.产品使用声明 质量保证 Evaluated by Western Blot in mouse e16 brain tissue lysate.
Western Blot Analysis: 0.5 µg/mL of this antibody detected Fox-3 on 10 µg of mouse e16 brain tissue lysate.使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at 2-8°C from date of receipt. 包装信息 数量 100 µg
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