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merck millipore,默克密理博,IHCR1001-6,Anti-Neuron-Specific Nuclear Protein Antibody, prediluted, clone A60
产品名称：Anti-Neuron-Specific Nuclear Protein Antibody, prediluted, clone A60
产品型号：IHCR1001-6
Anti-Neuron-Specific Nuclear Protein Antibody, prediluted, clone A60 detects level of Neuron-Specific Nuclear Protein & has been published & validated for use in IH(P).
merck millipore,默克密理博,IHCR1001-6,Anti-Neuron-Specific Nuclear Protein Antibody, prediluted, clone A60
- 产品介绍
- merck millipore,默克密理博,IHCR1001-6,Anti-Neuron-Specific Nuclear Protein Antibody, prediluted, clone A60
重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 Vrt, Av, Ch, Ft, H, M, Po, R, Pm, Sal IH(P) M Purified Monoclonal Antibody 描述 产品目录编号 IHCR1001-6 品牌系列 Chemicon®
商名 - Chemicon
描述 Anti-Neuron-Specific Nuclear Protein Antibody, prediluted, clone A60 Alternate Names - NeuN
背景信息 NeuN antibody (NEUronal Nuclei; clone A60) specifically recognizes the DNA-binding, neuron-specific protein NeuN, which is present in most CNS and PNS neuronal cell types of all vertebrates tested. NeuN protein distributions are apparently restricted to neuronal nuclei, perikarya and some proximal neuronal processes in both fetal and adult brain although, some neurons fail to be recognized by NeuN at all ages: INL retinal cells, Cajal-Retzius cells, Purkinje cells, inferior olivary and dentate nucleus neurons, and sympathetic ganglion cells are examples (Mullen et al., 1992; Wolf et al., 1996). Immunohistochemically detectable NeuN protein first appears at developmental timepoints that correspond with the withdrawal of the neuron from the cell cycle and/or with the initiation of terminal differentiation of the neuron (Mullen et al., 1992). Immunoreactivity appears around E9.5 in the mouse neural tube and is extensive throughout the developing nervous system by E12.5. Strong nuclear staining suggests a nuclear regulatory protein function; however, no evidence currently exists as to whether the NeuN protein antigen has a function in the distal cytoplasm or whether it is merely synthesized there before being transported back into the nucleus. No difference between protein isolated from purified nuclei and whole brain extract on immunoblots has been found (Mullen et al., 1992). 产品信息 格式 Purified 演示 Liquid diluted in PBS, pH 7.2 with stabilizers, 0.2% Tween 20, and 0.1% ProClin 300 as preservative. 应用 应用 Anti-Neuron-Specific Nuclear Protein Antibody, prediluted, clone A60 detects level of Neuron-Specific Nuclear Protein & has been published & validated for use in IH(P). 主要应用 - Immunohistochemistry (Paraffin)
应用说明 Antibody is prediluted and ready to use for Immunohistochemistry of formalin-fixed, paraffin-embedded tissues.
Pretreatment: Heat Induced Epitope Retrieval (HIER). Recommend Citrate Buffer, pH 6.0 (Cat. No. 21545). No signal was detected without Epitope retrieval.
Incubation: 30 minutes with IHC Select® Detection Kits.
NeuN, has been prediluted for use as the primary antibody with Chemicon's IHC Select® Detection Kits and Protocols (Catalog Nos. DAB050, DET-HP1000, APR050, and DET-APR1000), but other supplier's IHC detection systems may be used.生物信息 免疫原品种 Purified cell nuclei from mouse brain. 克隆 A60 宿主 Mouse 特异性 neuron-specific protein NeuN 品种反应性 VertebratesAvianChickenFerretHumanMousePigRatPrimateSalamander 抗体类型 Monoclonal Antibody 产品使用声明 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Maintain at 2-8°C. Refer to vial for expiration dating. 包装信息 数量 6 mL
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