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merck millipore,默克密理博,HTS066RTA,Ready-to-Assay™ Y2 Neuropeptide Receptor Frozen Cells
产品名称：Ready-to-Assay™ Y2 Neuropeptide Receptor Frozen Cells
产品型号：HTS066RTA
Human Y2 GPCR frozen cells for Calcium flux Assays, ligand binding FLIPR Assays.
merck millipore,默克密理博,HTS066RTA,Ready-to-Assay™ Y2 Neuropeptide Receptor Frozen Cells
- 产品介绍
重要规格表
应用说明 品种 宿主细胞 蛋白靶 Calcium flux assay, ligand binding assays Human Chem-1 Y2 描述 产品目录编号 HTS066RTA 商名 - Ready-to-Assay
描述 Ready-to-Assay™ Y2 Neuropeptide Receptor Frozen Cells 背景信息 Millipore’s Ready-to-Assay GPCR frozen cells are designed for simple, rapid calcium assays with no requirement for intensive cell culturing. Millipore has optimized the freezing conditions to provide cells with high viability and functionality post-thaw. The user simply thaws the cells and resuspends them in media, dispenses cell suspension into assay plates and, following over night recovery, assays for calcium response.
The NPY family consists of three 36-amino acid peptides, neuropeptide Y (NPY), peptide YY (PYY) and pancreatic polypeptide (PP), which bind to the NPY receptor family of G protein-coupled receptors. Five NPY receptors, Y1, Y2, Y4, Y5 and Y6, have been defined at the molecular level, and each signals primarily through Gi/o. Binding of NPY family peptides to NPY receptors mediates a variety of physiological effects, including promotion of food intake, decreased anxiety, inhibition of neurotransmitter and hormone release, vasoconstriction, and gut motility. Y2 is primarily expressed in the CNS, and it mediates presynaptic inhibition of neurotransmitter release (Michel et al., 1998). Chemicon's cloned human Y2-expressing cell line is made in the Chem-1 host, which supports high levels of recombinant Y2 expression on the cell surface and contains high levels of the promiscuous G protein Gα15 to enhance coupling of the receptor to the calcium signaling pathway. Thus, the cell line is an ideal tool for screening for antagonists of interactions between Y2 and its ligands.产品信息 部件 - Fifty (50) mL of Media Component.
- Pack contains 2 vials of mycoplasma-free cells, 1 ml per vial.
应用 应用 Human Y2 GPCR frozen cells for Calcium flux Assays, ligand binding FLIPR Assays. 应用说明 Calcium flux assay, ligand binding assays 生物信息 品种 Human GPCR类别 A 宿主细胞 Chem-1 蛋白靶 Y2 靶子系列 Neuropeptide Y 细胞系类型 - Ready-to-Assay
产品使用声明 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
- This product contains genetically modified organisms (GMO). Within the EU GMOs are regulated by Directives 2001/18/EC and 2009/41/EC of the European Parliament and of the Council and their national implementation in the member States respectively. This legislation obliges Merck-Millipore to request certain information about you and the establishment where the GMOs are being handled.
储存和货运信息 存储条件 Place cells in liquid nitrogen immediately upon receipt. 包装信息 数量 1 kit
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