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品种 宿主细胞 蛋白靶 Human Chem-1 CCR6 描述 产品目录编号 HTS011M 品牌系列 Chemicon®
商名 - Chemicon
- ChemiScreen
描述 ChemiSCREEN™ CCR6 Membrane Preparation 产品信息 格式 Membranes 应用 应用 Human CCR6 GPCR membrane prepation for Radioligand binding Assays. 生物信息 品种 Human 品种反应性 Human Entrez基因编号 - NM_031409.3
- NM_004367.5
Entrez基因汇总 This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. The gene is preferentially expressed by immature dendritic cells and memory T cells. The ligand of this receptor is macrophage inflammatory protein 3 alpha (MIP-3 alpha). This receptor has been shown to be important for B-lineage maturation and antigen-driven B-cell differentiation, and it may regulate the migration and recruitment of dentritic and T cells during inflammatory and immunological responses. Alternatively spliced transcript variants that encode the same protein have been described for this gene. 基因符号 - CMKBR6
- CCR6
- CKR-L3
- DRY6
- DRY-6
- BN-1
- CKR6
- GPR29
- DCR2
- GPR-CY4
- CD196
- CC-CKR-6
- STRL22
- GPRCY4
- CKRL3
- CCR-6
GPCR类别 A 宿主细胞 Chem-1 蛋白靶 CCR6 靶子系列 Chemokine UniProt编号 - P51684
UniProt汇总 FUNCTION: SwissProt: P51684 # Receptor for a C-C type chemokine. Binds to MIP-3- alpha/LARC and subsequently transduces a signal by increasing the intracellular calcium ions level.
SIZE: 374 amino acids; 42494 Da
SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein.
TISSUE SPECIFICITY: Spleen, lymph nodes, appendix, and fetal liver. Expressed in lymphocytes, T-cells and B-cells but not in natural killer cells, monocytes or granulocytes.
SIMILARITY: SwissProt: P51684 ## Belongs to the G-protein coupled receptor 1 family.产品使用声明 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
包装信息 数量 200 assays
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