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merck millipore,默克密理博,GF306,IGF-I Protein, Human Recombinant Animal Free
产品名称:IGF-I Protein, Human Recombinant Animal Free
产品型号:GF306
The Insulin-like growth factor I protein(or IGF-1 protein), also known as somatomedin C, is the dominant effector of growth hormone & is structurally homologous to proinsulin. Manufactured using all n More>>
merck millipore,默克密理博,GF306,IGF-I Protein, Human Recombinant Animal Free
- 产品介绍
重要规格表
来源 纯度 E. coli Product is endotoxin free (< 0.1ng/μg of protein (<1EU/μg) and greater than 98% pure by SDS-PAGE gel and HPLC analyses 描述 产品目录编号 GF306 描述 IGF-I Protein, Human Recombinant Animal Free Alternate Names - IGFI
- IGF-1
- IGF1
- Insulinlike Growth Factor I
- Insulinlike Growth Factor 1
- Mechano growth factor
- Somatomedin-C
背景信息 Insulinlike growth factor I, also known as somatomedin C, is the dominant effector of growth hormone and is structurally homologous to proinsulin. The IGFs are mitogenic polypeptide growth factors that stimulate the proliferation and survival of various cell types including muscle, bone, and cartilage tissue in vitro. IGFs are predominantly produced by the liver, although a variety of tissues produce the IGFs at distinctive times. The IGFs belong to the Insulin gene family, which also contains insulin and relaxin. The IGFs are similar by structure and function to insulin, but have a much higher growth-promoting activity than insulin. IGF-II expression is influenced by placenta lactogen, while IGF-I expression is regulated by growth hormone. Both IGF-I and IGF-II signal through the tyrosine kinase type I receptor (IGF-IR), but, IGF-II can also signal through the IGF-II/Mannose-6-phosphate receptor. Mature IGFs are generated by proteolytic processing of inactive precursor proteins, which contain N-terminal and C-terminal propeptide regions. Recombinant human IGF-I and IGF-II are globular proteins containing 70 and 67 amino acids, respectively, and 3 intra-molecular disulfide bonds. 产品信息 配方 演示 Product is filtered through a 0.2 micron filter before lyophilization. 应用 应用 The Insulin-like growth factor I protein(or IGF-1 protein), also known as somatomedin C, is the dominant effector of growth hormone & is structurally homologous to proinsulin. Manufactured using all non-animal reagents. 生物信息 纯度 Product is endotoxin free (< 0.1ng/μg of protein (<1EU/μg) and greater than 98% pure by SDS-PAGE gel and HPLC analyses 来源 E. coli 交叉反应性 Mouse, Rat, Horse, Pig, Cow, Sheep, Monkey, Chicken, Tiger Salamander, Bacteria, Frog Entrez基因编号 - NM_000618.2
UniProt编号 - P05019
产品使用声明 质量保证 Bioactivity assay: The ED50 was determined by a cell proliferation assay using FDC-P1 cells is ≤ 2.0 ng/ml, corresponding to a specific activity of ≥ 5 x 105 units/mg. 储存和货运信息 存储条件 Store at -20°C for up to 6 months from date of receipt. 包装信息 数量 100 µg
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