merck millipore,默克密理博,GF116,Hepatocyte Growth Factor Protein, Recombinant human

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merck millipore,默克密理博,GF116,Hepatocyte Growth Factor Protein, Recombinant human
产品名称：Hepatocyte Growth Factor Protein, Recombinant human
产品型号：GF116
The Human Hepatocyte Growth Factor (or HGF protein) is also known as Scatter Factor & Hepatopoeitin A.

merck millipore,默克密理博,GF116,Hepatocyte Growth Factor Protein, Recombinant human

产品介绍

merck millipore,默克密理博,GF116,Hepatocyte Growth Factor Protein, Recombinant human

重要规格表

主要应用	品种	来源	纯度
CULT	Human	Baculovirus infected High-5 cells	Greater than 98% by SDS-PAGE and HPLC analysis. Endotoxin level is less than 0.1 ng per μg (1EU/μg).

描述
产品目录编号	GF116
品牌系列	Chemicon®
商名	Chemicon
描述	Hepatocyte Growth Factor Protein, Recombinant human
概述	Human Hepatocyte Growth Factor (HGF) is also known as Scatter Factor and Hepatopoeitin A. HGF is a potent mitogen for mature parenchymal hepatocyte cells and acts as a growth factor for a broad spectrum of tissues and cell types. Activities of HGF include induction of cell proliferation, motility, morphogenesis, inhibition of cell growth, and enhancement of neuron survival. HGF is a crucial mitogen for liver regeneration processes, especially after partial hepatectomy and other liver injuries. Human and murine HGF are cross-reactive. GF116 is an 80 kDa disulfide-linked heterodimeric protein consisting of the alpha chain (463 amino acids) and the beta chain (234 amino acids).
Alternate Names	HGF

产品信息
演示	The sterile filtered solution was lyophilized from 0.1M L-arginine HCl, 10 mM Tris, pH 8.0, and 200 mM NaCl.

应用
应用	The Human Hepatocyte Growth Factor (or HGF protein) is also known as Scatter Factor & Hepatopoeitin A.
主要应用	Cell Culture

生物信息
纯度	Greater than 98% by SDS-PAGE and HPLC analysis. Endotoxin level is less than 0.1 ng per μg (1EU/μg).
来源	Baculovirus infected High-5 cells
品种	Human
特异活性	The ED(50) was determined by the dose-dependent stimulation of the proliferation of monkey 4MBr-5 cells was found to be in the range of 20.0-40.0 ng/ml.
Entrez基因编号	NM_001010934.1 NM_000601.4 NM_001010931.1 NM_001010932.1 NM_001010933.1
Entrez基因汇总	Hepatocyte growth factor regulates cell growth, cell motility, and morphogenesis by activating a tyrosine kinase signaling cascade after binding to the proto-oncogenic c-Met receptor. Hepatocyte growth factor is secreted by mesenchymal cells and acts as a multi-functional cytokine on cells of mainly epithelial origin. Its ability to stimulate mitogenesis, cell motility, and matrix invasion gives it a central role in angiogenesis, tumorogenesis, and tissue regeneration. It is secreted as a single inactive polypeptide and is cleaved by serine proteases into a 69-kDa alpha-chain and 34-kDa beta-chain. A disulfide bond between the alpha and beta chains produces the active, heterodimeric molecule. The protein belongs to the plasminogen subfamily of S1 peptidases but has no detectable protease activity. Alternative splicing of this gene produces multiple transcript variants encoding different isoforms.
基因符号	SF HGF F-TCF Hepatopoeitin-A HGFB HPTA
UniProt编号	P14210
UniProt汇总	FUNCTION: SwissProt: P14210 # HGF is a potent mitogen for mature parenchymal hepatocyte cells, seems to be an hepatotrophic factor, and acts as growth factor for a broad spectrum of tissues and cell types. It has no detectable protease activity. SIZE: 728 amino acids; 83134 Da SUBUNIT: Dimer of an alpha chain and a beta chain linked by a disulfide bond. SIMILARITY: SwissProt: P14210 ## Belongs to the peptidase S1 family. Plasminogen subfamily. & Contains 4 kringle domains. & Contains 1 PAN domain. & Contains 1 peptidase S1 domain.

产品使用声明
使用声明	Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

储存和货运信息
存储条件	The lyophilized protein is stable for a few weeks at room temperature, but best stored at -20°C. Reconstituted HGF should be stored in working aliquots at -20°C. We recommend a quick centrifugation of the vial followed by reconstitution in water to a concentration of 0.5 mg/mL. This solution can then be diluted into other buffers and stored at 4°C for 1 week or stored at -20°C for future use. Avoid repeated freeze/thaw cycles.

储存和货运信息

存储条件

The lyophilized protein is stable for a few weeks at room temperature, but best stored at -20°C. Reconstituted HGF should be stored in working aliquots at -20°C. We recommend a quick centrifugation of the vial followed by reconstitution in water to a concentration of 0.5 mg/mL. This solution can then be diluted into other buffers and stored at 4°C for 1 week or stored at -20°C for future use. Avoid repeated freeze/thaw cycles.