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品种反应性 主要应用 宿主 格式 抗体类型 R, H WB Rb Purified Polyclonal Antibody 描述 产品目录编号 07-524 品牌系列 Upstate
商名 - Upstate
描述 Anti-Spry2 Antibody 产品信息 格式 Purified 控制 - Positive Control Included: 3T3 Cell Lysate (12-305)
演示 Protein A Purified immunoglobulin in 30% glycerol, 0.07M Tris-glycine, pH 7.4, 0.105 M NaCl, 0.035% sodium azide as a preservative. 应用 应用 Detect Spry2 using this Anti-Spry2 Antibody validated for use in WB. 主要应用 - Western Blotting
生物信息 免疫原品种 Peptide corresponding to amino acids 26-39 of human SPROUTY2 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Rabbit 特异性 Recognizes SPROUTY2. 同种型 IgG 品种反应性 RatHuman 抗体类型 Polyclonal Antibody Entrez基因编号 - NM_005842
Entrez基因汇总 This gene encodes a protein belonging to the sprouty family. The encoded protein contains a carboxyl-terminal cysteine-rich domain essential for the inhibitory activity on receptor tyrosine kinase signaling proteins and is required for growth factor stimulated translocation of the protein to membrane ruffles. In primary dermal endothelial cells this gene is transiently upregulated in response to fibroblast growth factor two. This protein is indirectly involved in the non-cell autonomous inhibitory effect on fibroblast growth factor two signaling. The protein interacts with Cas-Br-M (murine) ectropic retroviral transforming sequence, and can function as a bimodal regulator of epidermal growth factor receptor/mitogen-activated protein kinase signaling. This protein may play a role in alveoli branching during lung development as shown by a similar mouse protein. 基因符号 - MGC23039
- SPRY2
- hSPRY2
- Spry-2
纯化方法 Protein A purfied UniProt编号 - O43597
UniProt汇总 FUNCTION: SwissProt: O43597 # May function as an antagonist of fibroblast growth factor (FGF) pathways and may negatively modulate respiratory organogenesis.
SIZE: 315 amino acids; 34688 Da
SUBCELLULAR LOCATION: Cytoplasm. Cell membrane. Note=Associated with microtubules in unstimulated cells but is translocated to the membrane ruffles in cells stimulated ith EGF (epidermal growth factor).
DOMAIN: SwissProt: O43597 The Cys-rich domain is responsible for the localization of the protein to the membrane ruffles.
SIMILARITY: Belongs to the sprouty family. & Contains 1 SPR (sprouty) domain.产品使用声明 质量保证 routinely evaluated by immunoblot in in RIPA lysates from HeLa and 3T3/A31 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Maintain for 2 years at -20°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. 包装信息 数量 200 µg
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下一件merck millipore产品：merck millipore,默克密理博,ABE498,Anti-Lysine-specific demethylase 7 Antibody
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