merck millipore,默克密理愽
  • merck millipore,默克密理博,GF069,Macrophage Inflammatory Protein-3 α Protein, Recombinant human

  • merck millipore,默克密理博,GF069,Macrophage Inflammatory Protein-3 α Protein, Recombinant human

    产品名称：Macrophage Inflammatory Protein-3 α Protein, Recombinant human
    产品型号：GF069
    The human macrophage inflammatory protein-3alpha (or MIP-3alpha protein, Exodus-3, LARC) is a member of the beta-chemokine (C-C) family of cytokines.

    merck millipore,默克密理博,GF069,Macrophage Inflammatory Protein-3 α Protein, Recombinant human

  • 产品介绍
  • merck millipore,默克密理博,GF069,Macrophage Inflammatory Protein-3 α Protein, Recombinant human

    重要规格表

    主要应用 品种 来源 纯度
    CULTHumanE.coliGreater than 98% by SDS-PAGE and HPLC analysis. Endotoxin level is less than 0.1 ng per μg (1EU/μg) of MIP-3alpha.
    描述
    产品目录编号 GF069
    品牌系列 Chemicon®
    商名
    • Chemicon
    描述 Macrophage Inflammatory Protein-3 α Protein, Recombinant human
    概述 Human macrophage inflammatory protein-3alpha (MIP-3alpha, Exodus-3, LARC) is a member of the beta-chemokine (C-C) family of cytokines. GF069 is an 8.0 kDa protein containing 70 amino acid residues.
    Alternate Names
    • MIP-3alpha
    产品信息
    演示 Lyophilized protein with no additives.
    应用
    应用 The human macrophage inflammatory protein-3alpha (or MIP-3alpha protein, Exodus-3, LARC) is a member of the beta-chemokine (C-C) family of cytokines.
    主要应用
    • Cell Culture
    生物信息
    纯度 Greater than 98% by SDS-PAGE and HPLC analysis. Endotoxin level is less than 0.1 ng per μg (1EU/μg) of MIP-3alpha.
    来源 E.coli
    品种 Human
    特异活性 The biological activity of human MIP-3a was determined by its ability to chemoattract human T cells using a concentration range of 10.0-100.0 ng/mL.
    Entrez基因编号
    • NM_145898.1
    • NM_005064.3
    Entrez基因汇总 This gene is one of several cytokine genes clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity on resting T lymphocytes and monocytes, lower activity on neutrophils and no activity on activated T lymphocytes. The protein is also a strong suppressor of colony formation by a multipotential hematopoietic progenitor cell line. In addition, the product of this gene is a potent agonist at CC chemokine receptor 1. Two alternatively spliced variants encoding different active isoforms have been identified.
    基因符号
    • SCYA23
    • CCL23
    • MIP3
    • Ckb-8-1
    • Ckb-8
    • CKB-8
    • CK-beta-8
    • MPIF1
    • CKb8
    • CK-BETA-8
    • MIP-3
    • MPIF-1
    • hmrp-2a
    UniProt编号
    • P55773
    UniProt汇总 FUNCTION: SwissProt: P55773 # Shows chemotactic activity for monocytes, resting T- lymphocytes, and neutrophils, but not for activated lymphocytes. Inhibits proliferation of myeloid progenitor cells in colony formation assays. This protein can bind heparin. Binds CCR1. CCL23(19-99), CCL23(22-99), CCL23(27-99), CCL23(30-99) are more potent chemoattractants than the small-inducible cytokine A23.
    SIZE: 120 amino acids; 13443 Da
    SUBCELLULAR LOCATION: Secreted.
    TISSUE SPECIFICITY: High levels in adult lung, liver, skeletal muscle and pancreas. Moderate levels in fetal liver, adult bone marrow and placenta. The short form is the major species and the longer form was detected only in very low abundance. CCL23(19-99), CCL23(22-99), CCL23(27-99), CCL23(30-99) are found in high levels in synovial fluids from rheumatoid patients.
    SIMILARITY: SwissProt: P55773 ## Belongs to the intercrine beta (chemokine CC) family.
    产品使用声明
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 The lyophilized powder, though stable at room temperature, is best stored at -20°C. Reconstitute in water to a concentration of 0.1-1.0 mg/mL. This solution can be diluted into other buffered solutions and stored at 4ºC for 1 week or at -20ºC for future use. Reconstituted human MIP-3alpha should be stored in undiluted aliquots at -20°C for up to 6 months.
    包装信息
    数量 20 µg

    merck millipore,默克密理博,GF069,Macrophage Inflammatory Protein-3 α Protein, Recombinant human

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