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品种 来源 纯度 Human Human NT4/5 expressed in E.coli Greater that 98% by SDS-PAGE and HPLC analysis. Endotoxin level is less than 0.1 ng per mg (1EU/mg) of NT-4. 描述 产品目录编号 GF032 品牌系列 Chemicon®
商名 - Chemicon
描述 Neurotrophin 4/5 概述 Neurotrophin-4 (NT-4/NT-5) is a potent neurotrophic factor which supports the growth and survivability of nerve and/or glial cells. The active form of human NT-4 is a dimer, formed by two identical 130 amino acid subunits, which is held together by strong hydrophobic interactions. Alternate Names - NT4/5
产品信息 演示 Lyophilized protein with no additives. 应用 应用 The Neurotrophin-4 protein (or NT-4/NT-5 protein) is a potent neurotrophic factor which supports the growth & survivability of nerve and/or glial cells. 应用说明 Concentration range for most in vitro applications is 0.5 to 100 ng/mL. Responding cells include (partial list): Nerve, glial cells. 生物信息 纯度 Greater that 98% by SDS-PAGE and HPLC analysis. Endotoxin level is less than 0.1 ng per mg (1EU/mg) of NT-4. 来源 Human NT4/5 expressed in E.coli 品种 Human 特异活性 Chemicon's human NT-4 is fully biologically active when compared to standards. The ED(50) as determined by the dose-dependent induction of choline acetyl transferase activity in rat basal forebrain primary septal cultures. Entrez基因编号 - NM_006179.3
Entrez基因汇总 This gene is a member of a family of neurotrophic factors, neurotrophins, that control survival and differentiation of mammalian neurons. The expression of this gene is ubiquitous and less influenced by environmental signals. While knock-outs of other neurotrophins including nerve growth factor, brain-derived neurotrophic factor, and neurotrophin 3 prove lethal during early postnatal development, NTF5-deficient mice only show minor cellular deficits and develop normally to adulthood. 基因符号 - NT4
- NTF5
- NT-4
- NTF4
- Neurotrophin-4
- NT-5
- NT5
- NT-4/5
UniProt编号 - P34130
UniProt汇总 FUNCTION: SwissProt: P34130 # Target-derived survival factor for peripheral sensory sympathetic neurons.
SIZE: 210 amino acids; 22427 Da
SUBCELLULAR LOCATION: Secreted.
TISSUE SPECIFICITY: Highest levels in prostate, lower levels in thymus, placenta, and skeletal muscle. Expressed in embryonic and adult tissues.
SIMILARITY: SwissProt: P34130 ## Belongs to the NGF-beta family.产品使用声明 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 The lyophilized powder, though stable at room temperature, is best stored desiccated below 0°C for up to 12 months after date of receipt. After a quick spin, reconstitute with sterile water to a concentration of 0.1-1.0 mg/mL. This solution can be diluted into other aqueous buffers. Reconstitute NT-4 should be stored in undiluted aliquots at -20°C for up to six months. 包装信息 数量 10 µg
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