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来源 纯度 E.coli Greater than 98% by SDS-PAGE analysis 描述 产品目录编号 GF031 品牌系列 Chemicon®
商名 - Chemicon
描述 Neurotrophin 3 概述 NT-3 is a potent neurotrophic factor which supports the growth and survivability of nerve and/or glial cells. The active form of human NT-3 is a dimer, formed by two 13.6 kDa polpeptide monomers (240 total amino acid residues), which is held together by strong hydrophobic interactions. Alternate Names - NT3
产品信息 演示 Lyophilized protein with no additives. 应用 应用 The Neurotrophin-3 protein (or NT-3 protein) is a potent neurotrophic factor which supports the growth & survivability of nerve and/or glial cells. 应用说明 Concentration range for most in vitro applications is 20-50 ng/mL. Responding cells are (partial list): Nerve, glial cells. 生物信息 纯度 Greater than 98% by SDS-PAGE analysis 来源 E.coli 特异活性 Milliprore's human NT-3 is fully biologically active when compared to standards. The ED50 as determined by the dose-dependent induction of choline acetyl transferase activity in rat basal forebrain primary septal cultures was found to be <= 50 ng/mL. Entrez基因编号 - NM_002527.4
- NM_001102654.1
Entrez基因汇总 The protein encoded by this gene is a member of the neurotrophin family, that controls survival and differentiation of mammalian neurons. This protein is closely related to both nerve growth factor and brain-derived neurotrophic factor. It may be involved in the maintenance of the adult nervous system, and may affect development of neurons in the embryo when it is expressed in human placenta. NTF3-deficient mice generated by gene targeting display severe movement defects of the limbs. The mature peptide of this protein is identical in all mammals examined including human, pig, rat and mouse. 基因符号 - NT-3
- NTF3
- NT3
- NGF2
- HDNF
- MGC129711
- NGF-2
UniProt编号 - P20783
UniProt汇总 FUNCTION: SwissProt: P20783 # Seems to promotes the survival of visceral and proprioceptive sensory neurons.
SIZE: 257 amino acids; 29355 Da
SUBCELLULAR LOCATION: Secreted.
TISSUE SPECIFICITY: Brain and peripheral tissues.
SIMILARITY: SwissProt: P20783 ## Belongs to the NGF-beta family.产品使用声明 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 The lyophilized powder, though stable at room temperature, is best stored desiccated below 0°C. Reconstitute with sterile water to a concentration of 100 ng/uL. This solution can be diluted into water or other buffered solutions. Reconstitute NT-3 should be stored in undiluted aliquots at -20°C for up to 6 months. 包装信息 数量 10 µg
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