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品种反应性 主要应用 宿主 格式 抗体类型 Po, H FC Rb Phycoerythrin Polyclonal Antibody 描述 产品目录编号 FCABS376PE 商名 - Milli-Mark
描述 Milli-Mark™ Anti-HMGB1/HMG-1-PE Antibody Alternate Names - high-mobility group box 1
- High mobility group protein 1
- Sulfoglucuronyl carbohydrate binding protein
- high mobility group box 1
- high-mobility group (nonhistone chromosomal) protein 1
背景信息 HMG-1 (High-Mobility-Group protein, amphoterin) is a highly conserved protein with more than 95% amino acid identity between rodent and human HMG-1. It is a prevalent non-histone chromatin component and a non-sequence specific DNA binding protein. HMG-1 consists of two homologous HMG boxes rich in basic amino acids and an acidic tail at the carboxy-terminus. HMG-1 is involved in the regulation of chromatin structure as well as being involved, either as positive or negative factors with various aspects of DNA replication, transcription, repair, and ligation. HMG-1, identified as a membrane associated protein termed “amphoterin,” mediates neurite outgrowth, tumor outgrowth, and metastasis. It participates in plasminogen activation and is recognized as a late mediator of endotoxin lethality in mice. 产品信息 格式 Phycoerythrin 控制 - HeLa cells
演示 Purified rabbit polyclonal IgG conjugated to PE in PBS with 0.1% sodium azide and 15 mg/mL BSA. 应用 应用 Milli-Mark Anti-HMGB1/HMG-1-PE Antibody is an antibody against HMGB1/HMG-1 for use in FC. 主要应用 - Flow Cytometry
生物信息 免疫原品种 HMGB1/HMG-1 protein purified from pig thymus glands. 宿主 Rabbit 特异性 Antibody recognizes Human HMGB1/HMG-1. 同种型 IgG 品种反应性 PigHuman Species Reactivity Note Tested and passed on Human. Predicted to react with Pig based on immunogen design. 抗体类型 Polyclonal Antibody Entrez基因编号 - NP_001004034
基因符号 - HMG3
- HMGB1
- HMG1
- Amphoterin
- DKFZp686A04236
纯化方法 Protein A Purified UniProt编号 - P12682
UniProt汇总 DNA binding proteins that associates with chromatin and has the ability to bend DNA. Binds preferentially single-stranded DNA. Involved in V(D)J recombination by acting as a cofactor of the RAG complex. Acts by stimulating cleavage and RAG protein binding at the 23 bp spacer of conserved recombination signal sequences (RSS). Heparin-binding protein that has a role in the extension of neurite-type cytoplasmic processes in developing cells 产品使用声明 质量保证 Evaluated by flow cytometry using HeLa cells. 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Maintain refrigerated at 2-8 °C protected from light in undiluted aliquots for up to 6 months from date of receipt. 包装信息 数量 100 tests
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