merck millipore,默克密理愽
  • merck millipore,默克密理博,407601,Interleukin-1 Receptor-Associated-Kinase-1/4 Inhibitor - CAS 509093-47-4 - Calbiochem

  • merck millipore,默克密理博,407601,Interleukin-1 Receptor-Associated-Kinase-1/4 Inhibitor - CAS 509093-47-4 - Calbiochem

    产品名称：Interleukin-1 Receptor-Associated-Kinase-1/4 Inhibitor - CAS 509093-47-4 - Calbiochem
    产品型号：407601
    The Interleukin-1 Receptor-Associated-Kinase-1/4 Inhibitor controls the activity of Interleukin-1 Receptor-Associated-Kinase-1/4. Primarily used for Phosphorylation & Dephosphorylation apps.

    merck millipore,默克密理博,407601,Interleukin-1 Receptor-Associated-Kinase-1/4 Inhibitor - CAS 509093-47-4 - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,407601,Interleukin-1 Receptor-Associated-Kinase-1/4 Inhibitor - CAS 509093-47-4 - Calbiochem

    重要规格表

    经验配方 CAS号
    C₂₀H₂₁N₅O₄509093-47-4
    描述
    概述 A cell-permeable benzimidazole compound that acts as a potent and selective inhibitor of interleukin-1 receptor-associated kinases (IC50 = 300 nM and 200 nM for IRAK-1 and -4). Shown to exhibit little activity against a panel of 27 other kinases (IC50 >10 µM), including lck and src. Also available as a 25 mM solution in DMSO (Cat. No. 407602).
    产品目录编号 407601
    品牌系列 Calbiochem®
    同义词 N-(2-Morpholinylethyl)-2-(3-nitrobenzoylamido)-benzimidazole, IRAK-1/4 Inhibitor
    参考
    参考 Bhattacharyya, S., et al. 2007. Am. J. Physiol. Gastrointest. Liver Physiol. 293, G429.
    Powers, J.P., et al. 2006. Bioorg. Med. Chem. Lett. 16, 2842.
    产品信息
    CAS号 509093-47-4
    具有ATP竞争性 N
    形式 Yellow crystalline solid
    Hill配方 C₂₀H₂₁N₅O₄
    化学配方 C₂₀H₂₁N₅O₄
    Molar Mass 395.4
    可逆 N
    结构配方图像
    生物信息
    主靶 Interleukin-1 receptor-associated kinases
    主靶IC50 300 nM and 200 nM for IRAK-1 and -4
    纯度 ≥98% by HPLC
    理化信息
    细胞可渗透 Y
    溶解度 DMSO
    安全信息
    R相 R: 20/21/22

    Harmful by inhalation, in contact with skin and if swallowed.
    S相 S: 36

    Wear suitable protective clothing.
    储存和货运信息
    货运代码 Ambient Temperature Only
    毒性 Harmful
    储存 -20°C
    避光 Protect from light
    无需冷冻 No
    特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
    包装信息
    惰性气体下包装 Packaged under inert gas

    merck millipore,默克密理博,407601,Interleukin-1 Receptor-Associated-Kinase-1/4 Inhibitor - CAS 509093-47-4 - Calbiochem

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