- 当前位置：首页 > >Merck Millipore > 生命科学研究
- 生命科学研究
-
-
merck millipore,默克密理博,FCABS326PE,Milli-Mark Anti-acetyl-Histone H4 Antibody-PE
产品名称：Milli-Mark Anti-acetyl-Histone H4 Antibody-PE
产品型号：FCABS326PE
Milli-Mark Anti-acetyl-Histone H4 Antibody-PE is a highly specific rabbit polyclonal antibody, that targets Histone H4 & has been tested in Flow Cytometry.
merck millipore,默克密理博,FCABS326PE,Milli-Mark Anti-acetyl-Histone H4 Antibody-PE
- 产品介绍
重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 H FC Rb Phycoerythrin Polyclonal Antibody 描述 产品目录编号 FCABS326PE 商名 - Milli-Mark
描述 Milli-Mark® Anti-acetyl-Histone H4 Antibody-PE Alternate Names - histone cluster 1, H4a
- H4 histone family, member A
- histone 1, H4a
背景信息 Histone H4 is one of the 5 main histone proteins involved in the structure of chromatin in eukaryotic cells. Featuring a main globular domain and a long N terminal tail H4 is involved with the structure of the nucleosomes of the 'beads on a string' structure. Acetylation of histone H4 occurs at several different lysine positions in the histone tail and is performed by a family of enzymes known as Histone Acetyl Transferases (HATs). 产品信息 格式 Phycoerythrin 控制 - HeLa cells
演示 Purified rabbit polyclonal IgG conjugated to PE in PBS with 0.1% sodium azide and 15 mg/mL BSA. 应用 应用 Milli-Mark® Anti-acetyl-Histone H4 Antibody-PE is a highly specific rabbit polyclonal antibody, that targets Histone H4 & has been tested in Flow Cytometry. 主要应用 - Flow Cytometry
生物信息 免疫原品种 Tetrahymena histone H4 acetylated on lysines 5, 8, 12, and 16. 宿主 Rabbit 特异性 Recognizes acetylated histone H4. Cross-reacts with acetylated histone H2B from Tetrahymena and weakly cross-reacts with acetylated histone H2B from HeLa cells. May crossreact with other acetylated proteins. 同种型 IgG 品种反应性 Human 抗体类型 Polyclonal Antibody Entrez基因编号 - XP_001016593
Entrez基因汇总 Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H4 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element [provided by RefSeq]. 基因符号 - HHF2
- HHF1
修改 - Acetylation
纯化方法 Protein A Purified UniProt编号 - P69152
UniProt汇总 FUNCTION: SwissProt: P62805 # Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
SIZE: 103 amino acids; 11367 Da
SUBUNIT: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.
SUBCELLULAR LOCATION: Nucleus.
PTM: Symmetric dimethylation on Arg-4 by the PRDM1/PRMT5 complex may play a crucial role in the germ-cell lineage (By similarity). & Ubiquitinated by the CUL4-DDB-RBX1 complex in response to ultraviolet irradiation. This may weaken the interaction between histones and DNA and facilitate DNA accessibility to repair proteins.
SIMILARITY: SwissProt: P62805 ## Belongs to the histone H4 family.产品使用声明 质量保证 Evaluated by flow cytometry using HeLa cells. 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Maintain refrigerated at 2-8 °C protected from light in undiluted aliquots for up to 6 months from date of receipt. 包装信息 数量 100 tests
上一件merck millipore产品：merck millipore,默克密理博,AB1847,Anti-C-X-C Chemokine Receptor 4 Antibody, extracellular loop
下一件merck millipore产品：merck millipore,默克密理博,HTS210RTA,Ready-to-Assay™ P2Y2 Purinergic Receptor Frozen Cells
相关产品
merck millipore,默克密理博,CC115,Chicken Tenascin
merck millipore,默克密理博,MERS00002,Millicell-ERS 电压电阻表
%5BMABC140_IHC(P)-ALL%5D.jpg "merck millipore,默克密理博,MABC140,Anti-ARC Antibody, clone 6F9.1")
merck millipore,默克密理博,MABC140,Anti-ARC Antibody, clone 6F9.1
merck millipore,默克密理博,AB1847,Anti-C-X-C Chemokine Receptor 4 Antibody, extracellular loop
merck millipore,默克密理博,HTS210RTA,Ready-to-Assay™ P2Y2 Purinergic Receptor Frozen Cells
merck millipore,默克密理博,09-821,Anti-KLF4 Antibody
merck millipore,默克密理博,311155,Dansyl Chloride - CAS 605-65-2 - Calbiochem
merck millipore,默克密理博,16-246,Anti-EGFR Antibody, neutralizing, clone LA1, Alexa Fluor 488
merck millipore,默克密理博,MR-015P-5D,EmbryoMax M2 Medium (1X), Powdered, with phenol red, 250ml