merck millipore,默克密理博,FCABS165A6,Milli-Mark™ Anti-MAPK 1/2 (tERK) Antibody, Alexa Fluor 647 Conjugate

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Merck Millipore 默克密理愽

品种反应性	主要应用	宿主	格式	抗体类型
H	FC	Rb	AlexaFluor®647	Polyclonal Antibody

描述
产品目录编号	FCABS165A6
商名	Milli-Mark
描述	Milli-Mark™ Anti-MAPK 1/2 (tERK) Antibody, Alexa Fluor 647 Conjugate
Alternate Names	MNK1 Extracellular signal-regulated kinase 1 ERK-1 Insulin-stimulated MAP2 kinase Mitogen-activated protein kinase 1 MAP kinase 1 MAPK 1 p44-ERK1 ERT2 MAP kinase isoform p44 p44 MAPK Microtubule-associated protein 2 kinase
背景信息	The extracellular signal-regulated kinases 1 and 2 (ERK1 and ERK2), also called MAPK1 and MAPK2, are members of the Mitogen Activated Protein Kinase (MAPK) family of proteins found in all eukaryotes. Because the 44 kDa ERK1 and the 42 kDa ERK2 are highly homologous and both function in the same protein kinase cascade, the two proteins are often referred to collectively as ERK1/2 or MAPK1/2. The MAPK1/2 signaling cascade has been shown to be a critical regulator of cell differentiation, cell physiology and neuronal function. Aberrant control of MAPK1/2 activity has been implicated in a variety of pathological conditions, including cancer and autoimmune diseases, and efficient study methods are in demand.

产品信息
格式	AlexaFluor®647
控制	Jurkat cells
演示	Purified rabbit polyclonal antibody conjugated to Alexa Fluor 647 in PBS buffer with 15mg/mL BSA and 0.1% Sodium Azide

应用
应用	Milli-Mark Anti-MAPK 1/2 (tERK) Antibody, Alexa Fluor 647 Conjugate detects level of MAPK 1/2 (tERK) & has been published & validated for use in FC.
主要应用	Flow Cytometry

生物信息
免疫原品种	KLH-conjugated linear peptide corresponding to rat MAPK 1/2 at the C-terminus.
表位	C-terminus
浓缩	Please refer to the Certificate of Analysis for the lot-specific concentration.
宿主	Rabbit
特异性	Antibody recognizes MAPK1/2. C-terminus.
品种反应性	Human
Species Reactivity Note	Tested and passed on Human.
抗体类型	Polyclonal Antibody
Entrez基因编号	NP_059043
Entrez基因汇总	Kinase involved in intracellular signalling; component of Mapk signalling pathway [RGD]
基因符号	ERT1 MAPK1 p38 ERK P42MAPK ERK2 p40 PRKM1 p41mapk PRKM2 MAPK2 p42-MAPK p41 ERK-2
纯化方法	Protein A purfied
UniProt编号	P21708
UniProt汇总	FUNCTION: Involved in both the initiation and regulation of meiosis, mitosis, and postmitotic functions in differentiated cells by phosphorylating a number of transcription factors such as ELK-1. Phosphorylates EIF4EBP1; required for initiation of translation. Phosphorylates microtubule-associated protein 2 (MAP2). Phosphorylates SPZ1. Phosphorylates heat shock factor protein 4 (HSF4) By similarity

产品使用声明
质量保证	Evaluated by flow cytometry using Jurkat cells
使用声明	Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

储存和货运信息
存储条件	Maintained refrigerated at 2-8°C from date of receipt. Protected from light in undiluted aliquots for 6 months from date of receipt.

包装信息
数量	100 tests

merck millipore,默克密理博,FCABS165A6,Milli-Mark™ Anti-MAPK 1/2 (tERK) Antibody, Alexa Fluor 647 Conjugate

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