merck millipore,默克密理博,AB5457,Anti-GABA A Receptor α4 Antibody, NT

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Merck Millipore 默克密理愽

品种反应性	主要应用	宿主	格式	抗体类型
R	WB	Rb	Affinity Purified	Polyclonal Antibody

描述
产品目录编号	AB5457
品牌系列	Chemicon®
商名	Chemicon
描述	Anti-GABA A Receptor α4 Antibody, NT

产品信息
格式	Affinity Purified
演示	Affinity purified immunoglobulin. Liquid in 10 mM HEPES, pH 7.5, with 150 mM NaCl, 100 μg/mL BSA and 50% glycerol.

应用
应用	This Anti-GABA A Receptor α4 Antibody, N-terminus is validated for use in IP, WB for the detection of GABA A Receptor α4.
主要应用	Western Blotting
应用说明	Western blot: 1:1,000 Optimal working dilutions must be determined by the end user.

生物信息
免疫原品种	Synthetic peptide from the N-terminus of rat GABA A receptor alpha4 subunit.
表位	N-terminus
浓缩	Please refer to the Certificate of Analysis for the lot-specific concentration.
宿主	Rabbit
特异性	GABA A receptor alpha4 subunit. The apparent molecular mass of the alpha4 subunit in rat brain membrane fractions is 64 kDa.
品种反应性	Rat
抗体类型	Polyclonal Antibody
Entrez基因编号	NM_000809.2
Entrez基因汇总	GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified.
基因符号	GABA GABRA4
UniProt编号	P48169
UniProt汇总	FUNCTION: SwissProt: P48169 # GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel. SIZE: 554 amino acids; 61640 Da SUBUNIT: Generally pentameric. There are five types of GABA(A) receptor chains: alpha, beta, gamma, delta, and rho. SUBCELLULAR LOCATION: Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. SIMILARITY: SwissProt: P48169 ## Belongs to the ligand-gated ionic channel (TC 1.A.9) family.

产品使用声明
使用声明	Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

储存和货运信息
存储条件	Maintain at -20°C in undiluted for up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles. Do not store in a self-defrosting freezer.

包装信息
数量	100 µL

merck millipore,默克密理博,AB5457,Anti-GABA A Receptor α4 Antibody, NT

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