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merck millipore,默克密理博,EZRMFGF21-26K,Rat / Mouse FGF-21 ELISA Kit
产品名称：Rat / Mouse FGF-21 ELISA Kit
产品型号：EZRMFGF21-26K
This Rat / Mouse FGF-21 ELISA Kit is used to measure & quantify FGF-21 levels in Metabolism & Inflammation & Immunology research.
merck millipore,默克密理博,EZRMFGF21-26K,Rat / Mouse FGF-21 ELISA Kit
- 产品介绍
重要规格表
可用的分析物 品种反应性 主要应用 检测方法 FGF-21 M, R ELISA Fluorescent, Colorimetric 描述 产品目录编号 EZRMFGF21-26K 描述 Rat / Mouse FGF-21 ELISA Kit 背景信息 Recent studies have demonstrated that fibroblast growth factor 21 (FGF-21), a liver derived protein, is able to increase glucose uptake, as well as lower plasma triglyceride levels in an insulin-independent manner. FGF-21 suppresses glucagon release, thereby increasing insulin sensitivity, and reduces the amount of insulin production by pancreatic β-cells. Unlike insulin, which works in a rapid, hormone-like manner, FGF-21 activity requires several hours, indicating changes in gene expression. No significant weight gain was observed when FGF-21 was injected into animals, and mice that had been genetically engineered to overexpress FGF-21 weighed less and had less adipose tissue than the normal controls.
Although considerable progress has been made in the understanding of the pathobiology of type 2 diabetes, as well in the development of new compounds for the treatment of diabetic patients, this disease remains a major global health concern. Consequently, Millipore is pleased to offer the Rat/Mouse FGF-21 ELISA kit for the quantification of FGF-21 in rat and mouse serum and plasma samples. The insulin-independent activities of FGF-21, as well as the absence of the weight gain effects of insulin, thiazolidinediones and other anti-diabetic drugs, distinguish it from current insulin-sensitizing drugs, making it a promising therapeutic.产品信息 检测方法 FluorescentColorimetric 精度（%） - Inter-assay: < 8 %
- Intra-assay: < 10%
应用 应用 This Rat / Mouse FGF-21 ELISA Kit is used to measure & quantify FGF-21 levels in Metabolism & Inflammation & Immunology research. 主要应用 - ELISA
应用说明 This is a 3-hour assay requiring 20 μL (in duplicate) of rat sample or 10µl (in duplicate) of mouse sample. 生物信息 特异性 Cross-reactivity to Human FGF-21: 39%
No significant cross-reactivity to the cytokines and metabolic hormones tested was observed.品种反应性 MouseRat 可用的分析物 - FGF-21
准确度 - Spike Recovery: 85 – 102 %
理化信息 稀释的线性 Please contact Technical Service for this information 标准曲线范围 - 50 – 12000 pg/mL
产品使用声明 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
包装信息 数量 96-well strip plate
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