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merck millipore,默克密理博,05-185,Anti-avian Src Antibody, clone EC10
产品名称：Anti-avian Src Antibody, clone EC10
产品型号：05-185
Anti-avian Src Antibody, clone EC10 detects level of avian Src & has been published & validated for use in IP, WB & IC.
merck millipore,默克密理博,05-185,Anti-avian Src Antibody, clone EC10
- 产品介绍
重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 Av ICC, WB M Purified Monoclonal Antibody 描述 产品目录编号 05-185 品牌系列 Upstate
商名 - Upstate
描述 Anti-avian Src Antibody, clone EC10 产品信息 格式 Purified 演示 0.1M Tris-glycine, pH 7.4, 0.15M NaCl, with 0.05% sodium azide 应用 应用 Anti-avian Src Antibody, clone EC10 detects level of avian Src & has been published & validated for use in IP, WB & IC. 主要应用 - Immunocytochemistry
- Western Blotting
生物信息 免疫原品种 Recombinant chicken pp60src 克隆 clone EC10 宿主 Mouse 特异性 specific only for avian Src; this antibody is excellent for distinguishing pp60src in cells transfected with v-src or c-src expression vectors. 同种型 IgG2b 品种反应性 Avian 抗体类型 Monoclonal Antibody Entrez基因编号 - NM_198291.1
- NM_005417.3
Entrez基因汇总 This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. The protein encoded by this gene is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-SRC kinase. Mutations in this gene could be involved in the malignant progression of colon cancer. Two transcript variants encoding the same protein have been found for this gene. 基因符号 - pp60c-src
- SRC
- c-src
- p60-Src
- SRC1
- c-SRC
- ASV
纯化方法 Protein G chromatography UniProt编号 - P12931
UniProt汇总 SIZE: 536 amino acids; 59835 Da
SUBUNIT: Interacts with DDEF1/ASAP1 via its SH3 domain. Interacts with CCPG1 (By similarity). Interacts with CDCP1, PELP1, TGFB1I1 and TOM1L2.
PTM: Phosphorylated on Tyr-530 by c-Src kinase (CSK). The phosphorylated form is termed pp60c-src. The phosphorylated tail interacts with the SH2 domain thereby repressing kinase activity.
SIMILARITY: SwissProt: P12931 ## Belongs to the protein kinase superfamily. Tyr protein kinase family. SRC subfamily. & Contains 1 protein kinase domain. & Contains 1 SH2 domain. & Contains 1 SH3 domain.产品使用声明 质量保证 routinely evaluated in (60kDa) on a RIPA lysate of chicken embryo fibroblasts (CEF) 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 2 years at -20°C 包装信息 数量 200 µg
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