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可用的分析物 品种反应性 主要应用 检测方法 Leptin M ELISA Colorimetric, Fluorescent 描述 产品目录编号 EZML-82K 描述 Mouse Leptin ELISA 背景信息 Leptin is synthesized in adipocytes as a 16 kDa molecule and the circulating level is directly proportional to the total amount of fat in the body. 产品信息 检测方法 ColorimetricFluorescent 精度（%） - Intra-assay: 1.1–1.8
- Inter-assay: 3.0–4.6
应用 应用 This Mouse Leptin ELISA is used to measure & quantify Leptin levels in Metabolism & Endocrine & Neuroscience research. 主要应用 - ELISA
应用说明 Room temperature, 4 hour assay 10 µL sample size 生物信息 品种反应性 Mouse 可用的分析物 - Leptin
Entrez基因汇总 This gene encodes a protein that is secreted by white adipocytes, and which plays a major role in the regulation of body weight. This protein, which acts through the leptin receptor, functions as part of a signaling pathway that can inhibit food intake and/or regulate energy expenditure to maintain constancy of the adipose mass. This protein also has several endocrine functions, and is involved in the regulation of immune and inflammatory responses, hematopoiesis, angiogenesis and wound healing. Mutations in this gene and/or its regulatory regions cause severe obesity, and morbid obesity with hypogonadism. This gene has also been linked to type 2 diabetes mellitus development. UniProt编号 - P41159
- P41160
UniProt汇总 FUNCTION: SwissProt: P41159 # May function as part of a signaling pathway that acts to regulate the size of the body fat depot. An increase in the level of LEP may act directly or indirectly on the CNS to inhibit food intake and/or regulate energy expenditure as part of a homeostatic mechanism to maintain constancy of the adipose mass.
SIZE: 167 amino acids; 18641 Da
SUBUNIT: Interacts with SIGLEC6.
SUBCELLULAR LOCATION: Secreted.
DISEASE:SwissProt: P41159 # Defects in LEP may be a cause of autosomal recessive obesity [MIM:601665].
SIMILARITY: SwissProt: P41159 ## Belongs to the leptin family.准确度 - 87–100%
理化信息 灵敏度 - 0.05 ng/mL
稀释的线性 100–111% 标准曲线范围 - 0.2–30 ng/mL
产品使用声明 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
包装信息 数量 96-well strip plate
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