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merck millipore,默克密理博,ABE95,Anti-PRDM12 Antibody
产品名称:Anti-PRDM12 Antibody
产品型号:ABE95
Use Anti-PRDM12 Antibody (Rabbit Polyclonal Antibody) validated in WB, ICC to detect PRDM12 also known as PR domain zinc finger protein 12, arginine methyltransferase.
merck millipore,默克密理博,ABE95,Anti-PRDM12 Antibody
- 产品介绍
重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 M, H ICC, WB Rb Affinity Purified Polyclonal Antibody 描述 产品目录编号 ABE95 描述 Anti-PRDM12 Antibody Alternate Names - PR domain family
- PR domain zinc finger protein 12
- PR domain-containing protein 12
- arg methyltransferase
- arginine methyltransferase
背景信息 Histone methylation occurs on arginine and lysine residues and is catalyzed by two families of proteins, the protein arginine methyltransferase family and the SET-domain-containing methyltransferase family. Five members have been identified in the arginine methyltransferase family. About 27 are grouped into the SET-domain family, and another 17 make up the PR domain family that is related to the SET domain family. The retinoblastoma protein-interacting zinc finger gene RIZ1 is a tumor suppressor gene and the founding member of the PR domain family. PRDM12 (PR domain zinc finger protein 12) also acts as a tumor suppressor and is linked to the pathogenesis of chronic myeloid leukemia. PRDM12 is also thought to play a role in transcriptional regulation. 产品信息 格式 Affinity Purified 控制 - Human liver tissue lysate.
演示 Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. 应用 应用 Use Anti-PRDM12 Antibody (Rabbit Polyclonal Antibody) validated in WB, ICC to detect PRDM12 also known as PR domain zinc finger protein 12, arginine methyltransferase. 主要应用 - Immunocytochemistry
- Western Blotting
应用说明 Immunocytochemistry Analysis: A 1:500 dilution from a representative lot detected PRDM12 in NIH/3T3 and A431 cells. 生物信息 免疫原品种 KLH-conjugated linear peptide corresponding to human PRDM12. 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Rabbit 品种反应性 MouseHuman Species Reactivity Note Demonstrated to react with Human and Mouse. 抗体类型 Polyclonal Antibody Entrez基因编号 - NP_067632
基因符号 - PFM9
- PRDM12
纯化方法 Affinity purified UniProt编号 - Q9H4Q4
UniProt汇总 FUNCTION: May be involved in transcriptional regulation.
SUBCELLULAR LOCATION: Nucleus (Potential).
SEQUENCE SIMILARITIES: Contains 3 C2H2-type zinc fingers. Contains 1 SET domain.产品使用声明 质量保证 Evaluated by Western Blot in human liver tissue lysate.
Western Blot Analysis: 3 μg/mL of this antibody detected PRDM12 on 10 µg of human liver tissue lysate.使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at 2-8°C from date of receipt. 包装信息 数量 100 µg
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