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重要规格表
可用的分析物 品种反应性 主要应用 检测方法 Proinsulin H ELISA Colorimetric, Fluorescent 描述 产品目录编号 EZHIPI-17K 描述 Human Intact Proinsulin ELISA 背景信息 Proinsulin, the precursor of insulin and C-peptide, is made by the beta cells of the pancreas. This kit measures only the intact form of human proinsulin 产品信息 检测方法 ColorimetricFluorescent 精度（%） - Intra-assay: 0.4–7.7
- Inter-assay: 3.3–9.0
应用 应用 This Human Intact Proinsulin ELISA is used to measure & quantify Proinsulin levels in Metabolism & Endocrine research. 主要应用 - ELISA
应用说明 50 μL sample volume 3 hour assay at room temperature 生物信息 品种反应性 Human 可用的分析物 - Proinsulin
Entrez基因编号 - NM_000207.2
Entrez基因汇总 After removal of the precursor signal peptide, proinsulin is post-translationally cleaved into two chains (peptide A and peptide B) that are covalently linked via two disulfide bonds. Binding of this mature form of insulin to the insulin receptor (INSR) stimulates glucose uptake. A variety of mutant alleles with changes in the coding region have been identified. There is a read-through gene, INS-IGF2, which overlaps with this gene at the 5' region and with the IGF2 gene at the 3' region. 基因符号 - insulin
- INS
- proinsulin
UniProt编号 - P01308
UniProt汇总 FUNCTION: SwissProt: P01308 # Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.
SIZE: 110 amino acids; 11981 Da
SUBUNIT: Heterodimer of a B chain and an A chain linked by two disulfide bonds.
SUBCELLULAR LOCATION: Secreted.
DISEASE:SwissProt: P01308 # Defects in INS are the cause of familial hyperproinsulinemia [MIM:176730].
SIMILARITY: SwissProt: P01308 ## Belongs to the insulin family.准确度 - 93–97%
理化信息 灵敏度 - 0.1 pM
稀释的线性 91–104% 标准曲线范围 - 0.5–100 pM
产品使用声明 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
包装信息 数量 96-well strip plate
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