merck millipore,默克密理愽
  • merck millipore,默克密理博,CBL555,Anti-CD34 Class III Antibody, clone 581

  • merck millipore,默克密理博,CBL555,Anti-CD34 Class III Antibody, clone 581

    产品名称：Anti-CD34 Class III Antibody, clone 581
    产品型号：CBL555
    This Anti-CD34 Class III Antibody, clone 581 is validated for use in FC for the detection of CD34 Class III.

    merck millipore,默克密理博,CBL555,Anti-CD34 Class III Antibody, clone 581

  • 产品介绍
  • merck millipore,默克密理博,CBL555,Anti-CD34 Class III Antibody, clone 581

    重要规格表

    品种反应性 主要应用 宿主 格式 抗体类型
    HFCMPurifiedMonoclonal Antibody
    描述
    产品目录编号 CBL555
    品牌系列 Chemicon®
    商名
    • Chemicon
    描述 Anti-CD34 Class III Antibody, clone 581
    产品信息
    格式 Purified
    演示 Protein G affinity chromatography. The monoclonal is presented at a concentration of 100μg/1ml in phosphate buffered saline containing 10mM sodium azide and 1mg/ml bovine serum albumin. We recommend that each laboratory determine an optimum working titre for use in its particular application.
    应用
    应用 This Anti-CD34 Class III Antibody, clone 581 is validated for use in FC for the detection of CD34 Class III.
    主要应用
    • Flow Cytometry
    应用说明 Study of the Class III CD34 epitope by FACS

    Optimal working dilutions must be determined by the end user.
    生物信息
    克隆 581
    宿主 Mouse
    特异性 Clone 581 reacts with the class III CD34 epitope is resistant to neuraminidase, chymopapain and glycoprotease.

    The antibody reacts with a single-chain 105-120 kDa heavily O-glycosylated transmembrane glycoprotein which is expressed on haematopoietic progenitor cells, vascular endothelium and some tissue fibroblasts. The intracellular chain of the CD34 antigen is a site of phosphorylation by activated protein kinase C suggesting a putative role in signal transduction. CD34 may also play a role in the adhesion of specific antigens to endothelium.
    同种型 IgG1
    品种反应性 Human
    抗体类型 Monoclonal Antibody
    Entrez基因编号
    • NM_001773.2
    • NM_001025109.1
    Entrez基因汇总 CD34 is a monomeric cell surface antigen with a molecular mass of approximately 110 kD that is selectively expressed on human hematopoietic progenitor cells.[supplied by OMIM]
    基因符号
    • CD34
    UniProt编号
    • P28906
    UniProt汇总 FUNCTION: SwissProt: P28906 # Possible adhesion molecule with a role in early hematopoiesis by mediating the attachment of stem cells to the bone marrow extracellular matrix or directly to stromal cells. Could act as a scaffold for the attachment of lineage specific glycans, allowing stem cells to bind to lectins expressed by stromal cells or other marrow components. Presents carbohydrate ligands to selectins.
    SIZE: 385 amino acids; 40716 Da
    SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane protein.
    TISSUE SPECIFICITY: Selectively expressed on hematopoietic progenitor cells and the small vessel endothelium of a variety of tissues.
    DEVELOPMENTAL STAGE: On early hematopoietic progenitor cells.
    PTM: Highly glycosylated. & Phosphorylated on serine residues by PKC.
    DISEASE:SwissProt: P28906 # Abnormal CD34 expression in leukemogenesis.
    SIMILARITY: SwissProt: P28906 ## Belongs to the CD34 family.
    产品使用声明
    销售限制 This product is not available for sale in the United States.
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 For use within 1 month of purchase store at +4°C, for long term storage aliquot antibody into small volumes and store at -20°C.
    包装信息
    数量 100 µg

    merck millipore,默克密理博,CBL555,Anti-CD34 Class III Antibody, clone 581

上一件merck millipore产品：merck millipore,默克密理博,ABE623,Anti-TARBP2 Antibody
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