merck millipore,默克密理愽
  • merck millipore,默克密理博,171588,Aβ₄₂ Fibrillogenesis Inhibitor III - Calbiochem

  • merck millipore,默克密理博,171588,Aβ₄₂ Fibrillogenesis Inhibitor III - Calbiochem

    产品名称：Aβ₄₂ Fibrillogenesis Inhibitor III - Calbiochem
    产品型号：171588
    The Aβ42 Fibrillogenesis Inhibitor III controls the biological activity of Aβ42Fibrillogenesis. This small molecule/inhibitor is primarily used for Neuroscience applications.

    merck millipore,默克密理博,171588,Aβ₄₂ Fibrillogenesis Inhibitor III - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,171588,Aβ₄₂ Fibrillogenesis Inhibitor III - Calbiochem

    重要规格表

    经验配方
    C₃₅H₄₆N₆O₈
    描述
    概述 A modified analog of Aβ42 Fibrillogenesis Inhibitor I (Cat. No. 171586) that crosses the blood-brain barrier and acts as a β-sheet breaker. Reported to increase neuronal survival and reduce brain inflammation in a transgenic mouse model of Alzheimer’s disease, probably due to a reduction in Aβ deposits. Displays greater stability against proteolytic degradation (t1/2 > 24 hours in human plasma and cerebrospinal fluid; ~ 37 minutes in blood).
    产品目录编号 171588
    品牌系列 Calbiochem®
    同义词 Amyloid β₄₂ Fibrillogenesis Inhibitor III, iAβ5p, Ac-LPFFD-NH₂
    参考
    参考 Permanne, B., et al. 2002. FASEB J. 16, 860.
    产品信息
    具有ATP竞争性 N
    形式 White solid
    Hill配方 C₃₅H₄₆N₆O₈
    化学配方 C₃₅H₄₆N₆O₈
    Molar Mass 678.8
    肽序列 Ac-Leu-Pro-Phe-Phe-Asp-NH₂
    可逆 N
    生物信息
    主靶 Reduction in Aβ deposits
    纯度 ≥95% by HPLC
    理化信息
    细胞可渗透 N
    溶解度 DMSO
    肽序列 Ac-Leu-Pro-Phe-Phe-Asp-NH₂
    储存和货运信息
    货运代码 Ambient Temperature Only
    毒性 Standard Handling
    储存 +2°C to +8°C
    无需冷冻 No
    特殊指南 Following reconstitution aliquot and freeze (-20°C). Stock solutions in DMSO are stable for up to 6 months at -20°C. Stock solutions in H₂O are stable for up to 1 month at -20°C.
    包装信息
    惰性气体下包装 Packaged under inert gas

    merck millipore,默克密理博,171588,Aβ₄₂ Fibrillogenesis Inhibitor III - Calbiochem

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