merck millipore,默克密理愽
  • merck millipore,默克密理博,CBL496,Anti-CD34 Class II Antibody, clone QBEND/10

  • merck millipore,默克密理博,CBL496,Anti-CD34 Class II Antibody, clone QBEND/10

    产品名称：Anti-CD34 Class II Antibody, clone QBEND/10
    产品型号：CBL496
    Anti-CD34 Class II Antibody, clone QBEND/10 is an antibody against CD34 Class II for use in FC, IP, IH, IH(P).

    merck millipore,默克密理博,CBL496,Anti-CD34 Class II Antibody, clone QBEND/10

  • 产品介绍
  • merck millipore,默克密理博,CBL496,Anti-CD34 Class II Antibody, clone QBEND/10

    重要规格表

    品种反应性 主要应用 宿主 格式 抗体类型
    Mk, HIHC, FCMPurifiedMonoclonal Antibody
    描述
    产品目录编号 CBL496
    品牌系列 Chemicon®
    商名
    • Chemicon
    描述 Anti-CD34 Class II Antibody, clone QBEND/10
    产品信息
    格式 Purified
    演示 The monoclonal is presented at a concentration of 100μg/1ml in phosphate buffered saline containing 10mM sodium azide and 1mg/ml bovine serum albumin. We recommend that each laboratory determine an optimum working titre for use in its particular application.
    应用
    应用 Anti-CD34 Class II Antibody, clone QBEND/10 is an antibody against CD34 Class II for use in FC, IP, IH, IH(P).
    主要应用
    • Immunohistochemistry
    • Flow Cytometry
    应用说明 Identification of haemopoietic progenitor cells

    Studies into the control mechanisms of early haemopoiesis

    Purification of haemopoietic cells from, for example, FACS

    The antibody reacts with both frozen and fixed tissue sections from vascular endothelium and stromal fibroblasts

    Immunohistochemistry in parraffin sections: Pretreatment is HIER with citrate buffer, pH 6.0.

    Optimal working dilutions must be determined by the end user.
    生物信息
    免疫原品种 Human endothelial vesicles
    克隆 QBEND/10
    宿主 Mouse
    特异性 The antibody recognizes a heavily glycosylated transmembrane protein: gp 105-120 kDa. The antigen is expressed on immature human haemopoietic precursor cells, capillary endothelial cells and human myeloid cells in the following categories: subsets of CFU-GEMM and BFU-E, all CFU-GM, granulocyte precursors, monocytes, myeloid leukaemias. This antibody recognizes the class II epitope showing resistance to neuraminidase enzyme cleavage.

    KNOWN SPECIES CROSS REACTIVITY: Positive with rhesus monkey peripheral blood leucocytes in flow cytometry.

    FUSION PARTNER: NSO myeloma cell line
    同种型 IgG1
    品种反应性 MonkeyHuman
    抗体类型 Monoclonal Antibody
    Entrez基因编号
    • NM_001773.2
    • NM_001025109.1
    Entrez基因汇总 CD34 is a monomeric cell surface antigen with a molecular mass of approximately 110 kD that is selectively expressed on human hematopoietic progenitor cells.[supplied by OMIM]
    基因符号
    • CD34
    UniProt编号
    • P28906
    UniProt汇总 FUNCTION: SwissProt: P28906 # Possible adhesion molecule with a role in early hematopoiesis by mediating the attachment of stem cells to the bone marrow extracellular matrix or directly to stromal cells. Could act as a scaffold for the attachment of lineage specific glycans, allowing stem cells to bind to lectins expressed by stromal cells or other marrow components. Presents carbohydrate ligands to selectins.
    SIZE: 385 amino acids; 40716 Da
    SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane protein.
    TISSUE SPECIFICITY: Selectively expressed on hematopoietic progenitor cells and the small vessel endothelium of a variety of tissues.
    DEVELOPMENTAL STAGE: On early hematopoietic progenitor cells.
    PTM: Highly glycosylated. & Phosphorylated on serine residues by PKC.
    DISEASE:SwissProt: P28906 # Abnormal CD34 expression in leukemogenesis.
    SIMILARITY: SwissProt: P28906 ## Belongs to the CD34 family.
    产品使用声明
    销售限制 This product is not available for sale in the United States.
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 For use within 1 month of purchase store at +4°C, for long term storage aliquot antibody into small volumes and store at -20°C.
    包装信息
    数量 100 µg

    merck millipore,默克密理博,CBL496,Anti-CD34 Class II Antibody, clone QBEND/10

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