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  • merck millipore,默克密理博,AB15708B,Anti-Beta III Tubulin, Biotin conjugate Antibody

  • merck millipore,默克密理博,AB15708B,Anti-Beta III Tubulin, Biotin conjugate Antibody

    产品名称：Anti-Beta III Tubulin, Biotin conjugate Antibody
    产品型号：AB15708B
    Anti-Beta III Tubulin, Biotin conjugate Antibody detects level of Beta III Tubulin & has been published & validated for use in ICC.

    merck millipore,默克密理博,AB15708B,Anti-Beta III Tubulin, Biotin conjugate Antibody

  • 产品介绍
  • merck millipore,默克密理博,AB15708B,Anti-Beta III Tubulin, Biotin conjugate Antibody

    重要规格表

    品种反应性 主要应用 宿主 格式 抗体类型
    M, R, HICCRbBiotinPolyclonal Antibody
    描述
    产品目录编号 AB15708B
    描述 Anti-Beta III Tubulin, Biotin conjugate Antibody
    Alternate Names
    • Beta III Tubulin
    • Tubulin beta-4
    • Tubulin beta-III
    • tubulin, beta 3
    • tubulin, beta, 4
    背景信息 Tubulin is one of several members of a small family of globular proteins which polymerize to form cytoskeletal structures called microtubules. The most common members of the tubulin family are α-tubulin and β-tubulin. Tubulin dimers, typically composed of α- and β-tubulin subunits, assemble onto microtubules forming large polymers. β-III tubulin is a unique microtubule subunit that is found expressed almost exclusively in neurons. Due to the unique expression pattern of β-III tubulin it is often utilized as a marker to identify neuronal cells from other brain cells such as glia which do not express it. β-III tubulin also serves as a cytoarchitectural marker since it is primarily found within neurite extensions.
    产品信息
    格式 Biotin
    控制
    • Rat E18 cortex cells
    演示 Purified rabbit polyclonal conjugated to Biotin in PBS with 0.1% sodium azide and 15 mg/mL BSA.
    应用
    应用 Anti-Beta III Tubulin, Biotin conjugate Antibody detects level of Beta III Tubulin & has been published & validated for use in ICC.
    主要应用
    • Immunocytochemistry
    生物信息
    免疫原品种 Synthetic peptide from human Beta III Tubulin
    宿主 Rabbit
    品种反应性 MouseRatHuman
    Species Reactivity Note Demonstrated to react with Rat. Predicted to react with Human and Mouse based on 100% sequence homology.
    抗体类型 Polyclonal Antibody
    Entrez基因编号
    • NP_006077
    Entrez基因汇总 This gene encodes a class III member of the beta tubulin protein family. Beta tubulins are one of two core protein families (alpha and beta tubulins) that heterodimerize and assemble to form microtubules. This protein is primarily expressed in neurons and may be involved in neurogenesis and axon guidance and maintenance. Mutations in this gene are the cause of congenital fibrosis of the extraocular muscles type 3. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 6.
    基因符号
    • beta-4
    • TUBB3
    • TUBB4
    • MC1R
    纯化方法 Affinity purified
    UniProt编号
    • Q13509
    UniProt汇总 FUNCTION: Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha-chain.

    SIZE: 450 amino acids; 50433 Da

    SUBUNIT: Dimer of alpha and beta chains.

    DOMAIN: The highly acidic C-terminal region may bind cations such as calcium.

    SIMILARITY: Belongs to the tubulin family.
    产品使用声明
    质量保证 Evaluated by Immunocytochemistry in rat E18 cortex cells.

    Immunocytochemistry Analysis: A 1:100 dilution of this antibody detected Beta III Tubulin in rat E18 cortex cells.
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 Stable for 1 year at 2-8°C from date of receipt.
    包装信息
    数量 100 µL

    merck millipore,默克密理博,AB15708B,Anti-Beta III Tubulin, Biotin conjugate Antibody

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