merck millipore,默克密理博,AG340,Epithelial Sodium Channel γ, control peptide for AB3534P

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Merck Millipore 默克密理愽

merck millipore,默克密理博,AG340,Epithelial Sodium Channel γ, control peptide for AB3534P
产品名称：Epithelial Sodium Channel γ, control peptide for AB3534P
产品型号：AG340

merck millipore,默克密理博,AG340,Epithelial Sodium Channel γ, control peptide for AB3534P

描述
产品目录编号	AG340
品牌系列	Chemicon®
商名	Chemicon
描述	Epithelial Sodium Channel γ, control peptide for AB3534P
概述	ENACgamma (Epithelial Sodium Channel gamma) control peptide for use with Catalog Number AB3534P. A 14 amino acid peptide sequence near the N-terminus of rat ENaC gamma.
Alternate Names	ENaC gamma

产品信息
演示	Liquid in PBS pH 7.4, containing 0.1% sodium azide.

应用
主要应用	Cell Function Assay
应用说明	Antibody blocking (AB3534P) ELISA Optimal working dilution must be determined by the end user.

生物信息
浓缩	1 mg/mL
品种	Rat
Entrez基因编号	NM_001039.3
基因符号	PHA1 SCNN1G SCNEG Gamma-ENaC ENaCg Gamma-NaCH ENaCgamma
UniProt编号	P51170
UniProt汇总	FUNCTION: SwissProt: P51170 # Sodium permeable non-voltage-sensitive ion channel inhibited by the diuretic amiloride. Mediates the electrodiffusion of the luminal sodium (and water, which follows osmotically) through the apical membrane of epithelial cells. Controls the reabsorption of sodium in kidney, colon, lung and sweat glands. Also plays a role in taste perception. SIZE: 649 amino acids; 74270 Da SUBUNIT: Heterotetramer of two alpha, one beta and one gamma subunit. A delta subunit can replace the alpha subunit. Interacts with the WW domains of NEDD4, NEDD4L, WWP1 and WWP2. SUBCELLULAR LOCATION: Apical cell membrane; Multi-pass membrane protein. Note=Apical membrane of epithelial cells. PTM: Phosphorylated on serine and threonine residues (By similarity). & Ubiquitinated; this targets individual subunits for endocytosis and proteasome-mediated degradation (By similarity). DISEASE: SwissProt: P51170 # Defects in SCNN1G are a cause of Liddle syndrome [MIM:177200]. It is an autosomal dominant disorder characterized by pseudoaldosteronism and hypertension associated with hypokalemic alkalosis. The disease is caused by constitutive activation of the renal epithelial sodium channel. SIMILARITY: SwissProt: P51170 ## Belongs to the amiloride-sensitive sodium channel family.

产品使用声明
使用声明	Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

储存和货运信息
存储条件	Store at -20°C in undiluted aliquots for up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles.

包装信息
数量	100 µg

merck millipore,默克密理博,AG340,Epithelial Sodium Channel γ, control peptide for AB3534P

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