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品种反应性 主要应用 宿主 格式 抗体类型 Ca, H IH(P) Rb Affinity Purified Polyclonal Antibody 描述 产品目录编号 ABT41 描述 Anti-Myosin XIX (Myo19) Antibody Alternate Names - Myosin head domain-containing protein 1
- Myosin-XIX
背景信息 Myosin XIX (Myo19) is the founding member of a novel class of myosin that associates with mitochondria. Both endogenous Myo19 and GFP-Myo19 exihibit localization to mitochondria. Myosins are actin-based motor molecules with ATPase activity. Myo19 is involved in actin-based mitochondrial motility. Myo19 mRNA is expressed in multiple tissues, and antibodies to human Myo19 detect an approximately 109 kDa band in multiple cell lines. 产品信息 格式 Affinity Purified 控制 - Human cardiac muscle tissue
演示 Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. 应用 应用 Anti-Myosin XIX (Myo19) Antibody detects level of Myosin XIX (Myo19) & has been published & validated for use in IH(P). 主要应用 - Immunohistochemistry (Paraffin)
生物信息 免疫原品种 KLH-conjugated linear peptide corresponding to human Myosin XIX (Myo19). 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Rabbit 品种反应性 CanineHuman Species Reactivity Note Demonstrated to react with Human.
Predicted to react with Canine based on 100% sequence homology. Other homologies: Rat and Mouse (92% sequence homology).抗体类型 Polyclonal Antibody Entrez基因编号 - NP_001028752
基因符号 - MYOHD1
- MYO19
纯化方法 Affinity Purified UniProt编号 - Q96H55
UniProt汇总 FUNCTION: Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Their highly divergent tails are presumed to bind to membranous compartments, which would be moved relative to actin filaments. MYO19 is involved in mitochondrial motility.
SUBCELLULAR LOCATION: Cytoplasm › cytoskeleton. Mitochondrion outer membrane. Note: Probably associated with the outer membrane via its N-terminal mitochondrial targeting region. TISSUE SPECIFICITY: Widely expressed in multiple tissues and cell lines.
SEQUENCE SIMILARITIES: Contains 2 IQ domains.
Contains 1 myosin head-like domain.
SEQUENCE CAUTION: The sequence BAD92272.1 differs from that shown. Reason: Erroneous initiation.产品使用声明 质量保证 Evaluated by Immunohistochemistry in human cardiac muscle tissue.
Immunohistochemistry Analysis: A 1:50 dilution of this antibody detected Myosin XIX (Myo19) in human cardiac muscle tissue.使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at 2-8°C from date of receipt. 包装信息 数量 100 µg
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