merck millipore,默克密理愽
  • merck millipore,默克密理博,239819,CXCR2 antagonist, Cpd 19 - CAS 473728-67-5 - Calbiochem

  • merck millipore,默克密理博,239819,CXCR2 antagonist, Cpd 19 - CAS 473728-67-5 - Calbiochem

    产品名称：CXCR2 antagonist, Cpd 19 - CAS 473728-67-5 - Calbiochem
    产品型号：239819
    The CXCR2 antagonist, Cpd 19, also referenced under CAS 473728-67-5, controls the biological activity of CXCR2.

    merck millipore,默克密理博,239819,CXCR2 antagonist, Cpd 19 - CAS 473728-67-5 - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,239819,CXCR2 antagonist, Cpd 19 - CAS 473728-67-5 - Calbiochem

    重要规格表

    经验配方 CAS号
    C₁₈H₂₁N₃O₄473728-67-5
    描述
    概述 A cell-permeable, cyclobutenedione derivative that acts as a potent antagonist of chemokine receptor CXCR2 (IL8RB) (IC50 = 8 nM). Reported to inhibit CXCR2-mediated chemotaxis in a CXCR2 expressing cell line (IC50 = 145 nM). Exhibits good stability in human and rat liver microsomal preparations (> 50% remaining after 30 min at 37°C).
    产品目录编号 239819
    品牌系列 Calbiochem®
    同义词 3-(2-(cyclopentylamino)-3,4-dioxocyclobut-1-enylamino)-2-hydroxy-N,N-dimethylbenzamide
    应用数据
    参考
    参考 Merritt, J., et al. 2006. Bioorg. Med. Chem. Lett. 16, 4107.
    产品信息
    CAS号 473728-67-5
    形式 Off-white solid
    Hill配方 C₁₈H₂₁N₃O₄
    化学配方 C₁₈H₂₁N₃O₄
    Molar Mass 343.38
    生物信息
    纯度 ≥95% by HPLC
    理化信息
    溶解度 DMSO
    储存和货运信息
    货运代码 Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
    毒性 Regulatory Review
    储存 -20°C
    避光 Protect from light
    无需冷冻 No
    特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
    包装信息
    惰性气体下包装 Packaged under inert gas

    merck millipore,默克密理博,239819,CXCR2 antagonist, Cpd 19 - CAS 473728-67-5 - Calbiochem

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