merck millipore,默克密理愽
  • merck millipore,默克密理博,ABT17,Anti-RGS4 Antibody

  • merck millipore,默克密理博,ABT17,Anti-RGS4 Antibody

    产品名称：Anti-RGS4 Antibody
    产品型号：ABT17
    Detect RGS4 using this Anti-RGS4 Antibody validated for use in WB.

    merck millipore,默克密理博,ABT17,Anti-RGS4 Antibody

  • 产品介绍
  • merck millipore,默克密理博,ABT17,Anti-RGS4 Antibody

    重要规格表

    品种反应性 主要应用 宿主 格式 抗体类型
    RWBRbSerumPolyclonal Antibody
    描述
    产品目录编号 ABT17
    描述 Anti-RGS4 Antibody
    Alternate Names
    • schizophrenia disorder 9
    • regulator of G-protein signaling 4
    • regulator of G-protein signalling 4
    背景信息 Regulator of G-protein signaling 4 (RGS4) is a GTPase activating protein belonging to the RGS family. This is a group of proteins known to act as GTPase activating proteins (GAPs), in order to regulate G protein signaling. RGS4 is highly expressed throughout the brain with highest expression observed in the prefrontal cortex, and some expression found in peripheral tissues such as the heart. RGS4 acts as a signal transduction inhibitor by inactivating G protein alpha subunits through the increase of their GTPase activity. Also, RGS4 serves to enhance Gi/o and Gq/11 protein GTPase activity and to expedite the conclusion of GPCR signaling. Various studies indicate a potential role for RGS4 in the regulation of various neurotransmitter systems, including those with putative involvement in schizophrenia. Mutations in the RGS4 gene lead to a lower presence of RGS4, linked to both Schizophrenia and Alzheimer’s symptoms.
    产品信息
    格式 Serum
    控制
    • PC12 cell lysate
    演示 Rabbit polyclonal serum containing 0.05% sodium azide.
    应用
    应用 Detect RGS4 using this Anti-RGS4 Antibody validated for use in WB.
    主要应用
    • Western Blotting
    应用说明 Western Blot Analysis: 1:1,000 dilution from a representative lot detected RGS4 on 10 µg of recombinant RGS4.
    生物信息
    免疫原品种 Recombinant protein corresponding to rat RGS4.
    宿主 Rabbit
    同种型 IgG
    品种反应性 Rat
    Species Reactivity Note Demonstrated to react with rat.
    抗体类型 Polyclonal Antibody
    Entrez基因编号
    • NP_058910
    Entrez基因汇总 Regulates G-protein coupled receptor signaling by accelerating the inactivation of active G-proteins; may regulate dopamine D2 receptor signaling [RGD].
    基因符号
    • RGS4
    • SCZD9
    • RGP4
    纯化方法 Unpurified
    UniProt编号
    • P49799
    UniProt汇总 FUNCTION: Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Activity on G(z)-alpha is inhibited by phosphorylation of the G-protein. Activity on G(z)-alpha and G(i)-alpha-1 is inhibited by palmitoylation of the G-protein.

    PTM: Either Cys-2 or Cys-12 or both are palmitoylated (by similarity).

    Phosphorylated by cyclic GMP-dependent protein kinase.

    SEQUENCE SIMILARITIES: Contains 1 RGS domain.
    产品使用声明
    质量保证 Evaluated by Western Blot in PC12 cell lysate.

    Western Blot Analysis: 1:1000 dilution of the antibody detected RGS4 in 10 µg of PC12 cell lysate.
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 Stable for 1 year at -20°C from date of receipt.
    Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
    包装信息
    数量 100 µL

    merck millipore,默克密理博,ABT17,Anti-RGS4 Antibody

上一件merck millipore产品：merck millipore,默克密理博,FCMAB145F,Milli-Mark Anti-CAF1 p150 -FITC Antibody, clone SS1, 1-3
下一件merck millipore产品：merck millipore,默克密理博,HTS174RTA,Ready-to-Assay™ Secretin Glucagon Receptor Frozen Cells


相关产品

merck millipore,默克密理博,05-1558,Anti-PI3 Kinase b Antibody, p110b, clone 8C3.2 merck millipore,默克密理博,05-1558,Anti-PI3 Kinase b Antibody, p110b, clone 8C3.2

merck millipore,默克密理博,178273,Aphidicolin - CAS 38966-21-1 - Calbiochem merck millipore,默克密理博,178273,Aphidicolin - CAS 38966-21-1 - Calbiochem

merck millipore,默克密理博,PP542-K,Mouse IgG (1g) merck millipore,默克密理博,PP542-K,Mouse IgG (1g)

merck millipore,默克密理博,MAB1921P,Anti-Laminin β1 Antibody, clone 4E10 merck millipore,默克密理博,MAB1921P,Anti-Laminin β1 Antibody, clone 4E10

merck millipore,默克密理博,FCMAB145F,Milli-Mark Anti-CAF1 p150 -FITC Antibody, clone SS1, 1-3 merck millipore,默克密理博,FCMAB145F,Milli-Mark Anti-CAF1 p150 -FITC Antibody, clone SS1, 1-3

merck millipore,默克密理博,HTS174RTA,Ready-to-Assay™ Secretin Glucagon Receptor Frozen Cells merck millipore,默克密理博,HTS174RTA,Ready-to-Assay™ Secretin Glucagon Receptor Frozen Cells

merck millipore,默克密理博,71229,pSTBlue-1 Perfectly Blunt Giga Cloning Kit - Novagen merck millipore,默克密理博,71229,pSTBlue-1 Perfectly Blunt Giga Cloning Kit - Novagen

merck millipore,默克密理博,9016,Lis/Pro Insulin merck millipore,默克密理博,9016,Lis/Pro Insulin

merck millipore,默克密理博,505487,PKM2 Activator IV, TEPP-46 - Calbiochem merck millipore,默克密理博,505487,PKM2 Activator IV, TEPP-46 - Calbiochem

merck millipore,默克密理博,MABC176,Anti-LC3A/B (NT) Antibody, clone EP1983Y, rabbit monoclonal merck millipore,默克密理博,MABC176,Anti-LC3A/B (NT) Antibody, clone EP1983Y, rabbit monoclonal


whatman,沃特曼,nalgene,耐洁,merck millipore,默克密理愽,sartorius,赛多利斯,pall,颇尔
thermo fisher,赛默飞世尔,GE,MN,macherey-nagel,advantec,wheaton,brand,普兰德,welch,airtech


上海羽令过滤器材有限公司版权所有 Copyright ©  www.yl-guolv.com  Powered by 羽令集团—信息技术部