• merck millipore,默克密理博,9016,Lis/Pro Insulin
  • merck millipore,默克密理博,9016,Lis/Pro Insulin

    产品名称:Lis/Pro Insulin
    产品型号:9016
    Iodinated Human Lis/Pro insulin -HPLC purified & prepared fresh monthly.

    merck millipore,默克密理博,9016,Lis/Pro Insulin

  • 产品介绍
  • merck millipore,默克密理博,9016,Lis/Pro Insulin

    描述
    产品目录编号 9016
    描述 Lis/Pro Insulin
    背景信息 These iodinated hormonos are HPLC purified and prepared fresh monthly.
    应用
    应用 Iodinated Human Lis/Pro insulin -HPLC purified & prepared fresh monthly.
    应用说明 appropriate label hydrating buffer if kit replacement or assay buffer of choice
    生物信息
    Entrez基因编号
    • NM_000207.2
    Entrez基因汇总 After removal of the precursor signal peptide, proinsulin is post-translationally cleaved into two chains (peptide A and peptide B) that are covalently linked via two disulfide bonds. Binding of this mature form of insulin to the insulin receptor (INSR) stimulates glucose uptake. A variety of mutant alleles with changes in the coding region have been identified. There is a read-through gene, INS-IGF2, which overlaps with this gene at the 5' region and with the IGF2 gene at the 3' region.
    基因符号
    • insulin
    • INS
    • proinsulin
    标签 125Iodine
    UniProt编号
    • P01308
    UniProt汇总 FUNCTION: SwissProt: P01308 # Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.
    SIZE: 110 amino acids; 11981 Da
    SUBUNIT: Heterodimer of a B chain and an A chain linked by two disulfide bonds.
    SUBCELLULAR LOCATION: Secreted.
    DISEASE:SwissProt: P01308 # Defects in INS are the cause of familial hyperproinsulinemia [MIM:176730].
    SIMILARITY: SwissProt: P01308 ## Belongs to the insulin family.
    理化信息
    放射性 <3 μCi
    储存和货运信息
    存储条件 2–8 °C
    包装信息
    数量 250 tubes

    merck millipore,默克密理博,9016,Lis/Pro Insulin

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