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描述 产品目录编号 9016 描述 Lis/Pro Insulin 背景信息 These iodinated hormonos are HPLC purified and prepared fresh monthly. 应用 应用 Iodinated Human Lis/Pro insulin -HPLC purified & prepared fresh monthly. 应用说明 appropriate label hydrating buffer if kit replacement or assay buffer of choice 生物信息 Entrez基因编号 - NM_000207.2
Entrez基因汇总 After removal of the precursor signal peptide, proinsulin is post-translationally cleaved into two chains (peptide A and peptide B) that are covalently linked via two disulfide bonds. Binding of this mature form of insulin to the insulin receptor (INSR) stimulates glucose uptake. A variety of mutant alleles with changes in the coding region have been identified. There is a read-through gene, INS-IGF2, which overlaps with this gene at the 5' region and with the IGF2 gene at the 3' region. 基因符号 - insulin
- INS
- proinsulin
标签 125Iodine UniProt编号 - P01308
UniProt汇总 FUNCTION: SwissProt: P01308 # Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.
SIZE: 110 amino acids; 11981 Da
SUBUNIT: Heterodimer of a B chain and an A chain linked by two disulfide bonds.
SUBCELLULAR LOCATION: Secreted.
DISEASE:SwissProt: P01308 # Defects in INS are the cause of familial hyperproinsulinemia [MIM:176730].
SIMILARITY: SwissProt: P01308 ## Belongs to the insulin family.理化信息 放射性 <3 μCi 储存和货运信息 存储条件 2–8 °C 包装信息 数量 250 tubes
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