merck millipore,默克密理愽
  • merck millipore,默克密理博,178273,Aphidicolin - CAS 38966-21-1 - Calbiochem

  • merck millipore,默克密理博,178273,Aphidicolin - CAS 38966-21-1 - Calbiochem

    产品名称：Aphidicolin - CAS 38966-21-1 - Calbiochem
    产品型号：178273
    A cell-permeable tetracyclic diterpene antibiotic that acts as a cell synchronization agent.

    merck millipore,默克密理博,178273,Aphidicolin - CAS 38966-21-1 - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,178273,Aphidicolin - CAS 38966-21-1 - Calbiochem

    重要规格表

    经验配方 CAS号
    C₂₀H₃₄O₄38966-21-1
    描述
    概述 A cell-permeable tetracyclic diterpene antibiotic that acts as a cell synchronization agent. Blocks the cell cycle at early S-phase. Specific inhibitor of DNA polymerase α and δ in eukaryotic cells and in some viruses. Potentiates apoptosis induced by arabinosyl nucleosides in leukemia cell lines. Also induces apoptosis in HeLa S3 cells, but inhibits vincristine-induced apoptosis in the p53-negative human prostate cancer cell line PC-3. Also available as a 30 mM solution in DMSO (Cat. No. 504744).
    产品目录编号 178273
    品牌系列 Calbiochem®
    参考
    参考 Borner, M.M., et al. 1995. Cancer Res. 55, 2122.
    Poluha, W., et al. 1995. Oncogene 10, 185.
    Urbani, L., et al. 1995. Exp. Cell Res. 219, 159.
    Schimke, R.T., et al. 1994. Philos. Trans. R. Soc. London. B. Biol. Sci. 345, 311.
    Kuwakado, K., et al. 1993. Biochem. Pharmacol. 46, 1909.
    Hubermann, J.A. 1981. Cell 23, 647.
    产品信息
    CAS号 38966-21-1
    具有ATP竞争性 N
    形式 White solid
    Hill配方 C₂₀H₃₄O₄
    化学配方 C₂₀H₃₄O₄
    Molar Mass 338.5
    可逆 N
    结构配方图像
    生物信息
    主靶 DNA polymerase α, DNA polymerase δ
    纯度 ≥98% by TLC
    理化信息
    细胞可渗透 Y
    溶解度 DMSO, EtOH, or MeOH
    GHS安全信息
    RTECS PB9185000
    储存和货运信息
    货运代码 Ambient Temperature Only
    毒性 Standard Handling
    储存 +2°C to +8°C
    无需冷冻 No
    特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 2 months at -20°C.

    merck millipore,默克密理博,178273,Aphidicolin - CAS 38966-21-1 - Calbiochem

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