merck millipore,默克密理愽
  • merck millipore,默克密理博,05-1558,Anti-PI3 Kinase b Antibody, p110b, clone 8C3.2

  • merck millipore,默克密理博,05-1558,Anti-PI3 Kinase b Antibody, p110b, clone 8C3.2

    产品名称：Anti-PI3 Kinase b Antibody, p110b, clone 8C3.2
    产品型号：05-1558
    This Anti-PI3 Kinase b Antibody, p110b, clone 8C3.2 is validated for use in WB, IC for the detection of PI3 Kinase b.

    merck millipore,默克密理博,05-1558,Anti-PI3 Kinase b Antibody, p110b, clone 8C3.2

  • 产品介绍
  • merck millipore,默克密理博,05-1558,Anti-PI3 Kinase b Antibody, p110b, clone 8C3.2

    重要规格表

    品种反应性 主要应用 宿主 格式 抗体类型
    M, R, HICC, WBMPurifiedMonoclonal Antibody
    描述
    产品目录编号 05-1558
    Replaces 04-400
    描述 Anti-PI3 Kinase b Antibody, p110b, clone 8C3.2
    Alternate Names
    • PI3 kinase b
    • PI3-kinase p110 subunit beta
    • PtdIns-3-kinase p110
    • phosphatidylinositol 3-kinase, catalytic, beta polypeptide
    • phosphoinositide-3-kinase, catalytic, beta polypeptide
    • PI3K beta
    • PI3 K beta
    背景信息 PI3 Kinase (Phosphatidylinositol 3-Kinase) is responsible for phosphorylation of the 3 position of the inositol ring of PI(4,5)P2, to generate PI(3,4,5)P3, a potent second messenger required for survival signaling, and insulin action. PI3 Kinase is a heterodimeric complex composed of an 85 kDa regulatory subunit and a 110 kDa catalytic subunit. Tyrosine phosphorylation of growth factor receptors creates docking sites for binding of p85 (through its SH2 domains) on the receptors; p85 brings with it p110, which is then proximal to its phospho-lipid substrate on the membrane. PI3 Kinase is also activated by Ras, and by the β:γ subunits of heterotrimeric G-proteins. PI3 Kinase is inhibitable by wortmannin, a useful tool for the study of the PI3 Kinase signaling pathway.
    产品信息
    格式 Purified
    控制
    • PC-12 cell lysate
    演示 Purified mouse monoclonal IgMκ in buffer containing PBS with 0.05% sodium azide.
    应用
    应用 This Anti-PI3 Kinase b Antibody, p110b, clone 8C3.2 is validated for use in WB, IC for the detection of PI3 Kinase b.
    主要应用
    • Immunocytochemistry
    • Western Blotting
    应用说明 Immunocytochemistry Analysis: A 1:500 dilution positively stained NIH3T3 cell lysate.
    生物信息
    免疫原品种 KLH-conjugated linear peptide corresponding to the N-terminus of human PI3 Kinase b.
    表位 N-terminus
    克隆 8C3.2
    浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration.
    宿主 Mouse
    特异性 This antibody recognizes PI3 Kinase b at the N-terminus.
    同种型 IgMκ
    品种反应性 MouseRatHuman
    Species Reactivity Note Demonstrated to react with human, mouse, and rat.
    抗体类型 Monoclonal Antibody
    Entrez基因编号
    • NP_006210
    Entrez基因汇总 Phosphoinositide 3-kinases (PI3Ks) phosphorylate the 3-prime OH position of the inositol ring of inositol lipids. They have been implicated as participants in signaling pathways regulating cell growth by virtue of their activation in response to various mitogenic stimuli. PI3Ks are composed of a 110-kD catalytic subunit, such as PIK3CB, and an 85-kD adaptor subunit (Hu et al., 1993 [PubMed 8246984]).[supplied by OMIM].
    基因符号
    • PIK3C1
    • PIK3CB
    • PI3Kbeta
    纯化方法 Ion Exchange
    UniProt编号
    • P42338
    UniProt汇总 FUNCTION: Phosphorylates PtdIns, PtdIns4P and PtdIns(4,5)P2 with a preference for PtdIns(4,5)P2.

    CATALYTIC ACTIVITY: ATP + 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate = ADP + 1-phosphatidyl-1D-myo-inositol 3,4,5-trisphosphate.

    PATHWAY: Phospholipid metabolism; phosphatidylinositol phosphate biosynthesis.

    SUBUNIT STRUCTURE: Heterodimer of a p110 (catalytic) and a p85 (regulatory) subunit.

    TISSUE SPECIFICITY: Expressed ubiquitously.

    SEQUENCE SIMILARITIES: Belongs to the PI3/PI4-kinase family.

    Contains 1 PI3K/PI4K domain.
    产品使用声明
    质量保证 Evaluated by Western Blot in PC-12 cell lysate.

    Western Blot Analysis: 0.5 µg/mL of this antibody detected PI3 Kinase b on 10 µg of PC-12 cell lysate.
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 Stable for 1 year at 2-8°C from date of receipt.
    包装信息
    数量 100 µg

    merck millipore,默克密理博,05-1558,Anti-PI3 Kinase b Antibody, p110b, clone 8C3.2

上一件merck millipore产品：merck millipore,默克密理博,IM51,Anti-MMP-2 (Ab-4) Mouse mAb (75-7F7)
下一件merck millipore产品：merck millipore,默克密理博,178273,Aphidicolin - CAS 38966-21-1 - Calbiochem


相关产品

merck millipore,默克密理博,NS106,Brain Blot, Adult Mouse merck millipore,默克密理博,NS106,Brain Blot, Adult Mouse

merck millipore,默克密理博,SF-2341,TAL1; Human, Cyanine 3 RNA Detection Probe,SmartFlare merck millipore,默克密理博,SF-2341,TAL1; Human, Cyanine 3 RNA Detection Probe,SmartFlare

merck millipore,默克密理博,171608,Anti-β-Amyloid₄₀ (FCA3340) Rabbit pAb merck millipore,默克密理博,171608,Anti-β-Amyloid₄₀ (FCA3340) Rabbit pAb

merck millipore,默克密理博,MACL09625,MultiScreen 装柱器，25 µL，黑色，铝制，非无菌 merck millipore,默克密理博,MACL09625,MultiScreen 装柱器，25 µL，黑色，铝制，非无菌

merck millipore,默克密理博,IM51,Anti-MMP-2 (Ab-4) Mouse mAb (75-7F7) merck millipore,默克密理博,IM51,Anti-MMP-2 (Ab-4) Mouse mAb (75-7F7)

merck millipore,默克密理博,178273,Aphidicolin - CAS 38966-21-1 - Calbiochem merck millipore,默克密理博,178273,Aphidicolin - CAS 38966-21-1 - Calbiochem

merck millipore,默克密理博,PP542-K,Mouse IgG (1g) merck millipore,默克密理博,PP542-K,Mouse IgG (1g)

merck millipore,默克密理博,MAB1921P,Anti-Laminin β1 Antibody, clone 4E10 merck millipore,默克密理博,MAB1921P,Anti-Laminin β1 Antibody, clone 4E10

merck millipore,默克密理博,FCMAB145F,Milli-Mark Anti-CAF1 p150 -FITC Antibody, clone SS1, 1-3 merck millipore,默克密理博,FCMAB145F,Milli-Mark Anti-CAF1 p150 -FITC Antibody, clone SS1, 1-3

merck millipore,默克密理博,ABT17,Anti-RGS4 Antibody merck millipore,默克密理博,ABT17,Anti-RGS4 Antibody


whatman,沃特曼,nalgene,耐洁,merck millipore,默克密理愽,sartorius,赛多利斯,pall,颇尔
thermo fisher,赛默飞世尔,GE,MN,macherey-nagel,advantec,wheaton,brand,普兰德,welch,airtech


上海羽令过滤器材有限公司版权所有 Copyright ©  www.yl-guolv.com  Powered by 羽令集团—信息技术部