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品种反应性 主要应用 宿主 格式 抗体类型 R, H IHC, WB Rb Affinity Purified Polyclonal Antibody 描述 产品目录编号 ABN645 描述 Anti-RIM 2 Antibody Alternate Names - Rab-3-interacting protein 3
- Regulating synaptic membrane exocytosis protein 2
- Rab-3-interacting molecule 2
- RIM 2
背景信息 Rab3-interacting molecules (RIMs) are synaptic proteins necessary for neuronal transmission and plasticity. RIM 1 and RIM 2 proteins are expressed in overlapping but distinct patterns throughout the brain. While the ablation of either gene was not lethal in mice, the deletion of both resulted in postnatal mortality. This lethality is due to a defect in neurotransmitter release; synapses without RIM proteins can still release neurotransmitters but are unable to do so in response to normal Ca2+ triggers. Like RIM 1, RIM 2 is thought to be an effector protein for Rab3, binding to Rab3 on synaptic vesicles in a GTP-dependent manner. 产品信息 格式 Affinity Purified 演示 Purified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide. 应用 应用 Anti-RIM 2 Antibody is an antibody against RIM 2 for use in western blotting, IHC & immunofluorescence. 主要应用 - Immunohistochemistry
- Western Blotting
应用说明 Immunohistochemistry Analysis: 5 μg/mL from a representative lot detected RIM 2 in human brain tissue.
Immunofluorescence Analysis: 20 μg/mL from a representative lot detected RIM 2 in human brain cells.
生物信息 免疫原品种 KLH-conjugated synthetic peptide corresponding to the center region of human RIM 2. 表位 center region 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Rabbit 特异性 This antibody may recognize many isoforms and is predicted to have no cross-reactivity to other RIM proteins. 品种反应性 RatHuman 抗体类型 Polyclonal Antibody 基因符号 - RIM2
- RIMS2
- RAB3IP3
纯化方法 Antigen Affinity purified UniProt编号 - Q9UQ26
产品使用声明 质量保证 Evaluated by Western Blotting in rat brain tissue lysate with and without blocking peptide.
Western Blotting Analysis: 1 μg/mL of this antibody detected RIM 2 in rat brain tissue lysate with and without blocking peptide.使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at 2-8°C from date of receipt. 包装信息 数量 100 µg
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