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品种反应性 主要应用 宿主 格式 抗体类型 H WB Rb Serum Polyclonal Antibody 描述 产品目录编号 AB10305 品牌系列 Chemicon®
商名 - Chemicon
描述 Anti-FXR-B Antibody Alternate Names - farnesoid X receptor
背景信息 The farnesoid X receptor (FXR) is a member of the nuclear receptor superfamily and is known to play a key role in bile acid homeostasis. It does through the regulation of key genes involved in bile acid synthesis, metabolism and transport. 产品信息 格式 Serum 演示 Raw rabbit serum with 0.1% sodium azide. 应用 应用 Detect FXR-B using this Anti-FXR-B Antibody validated for use in WB. 主要应用 - Western Blotting
应用说明 Suggested dilutions:
Western Blot: 1:5000生物信息 免疫原品种 Recombinant human hFXR-B 宿主 Rabbit 同种型 IgG2b 品种反应性 Human 抗体类型 Polyclonal Antibody Entrez基因编号 - NM_005123.2
基因符号 - FXRA
- NR1H4
- HRR1
- MGC163445
- FXR
- HRR-1
- RIP14
- BAR
UniProt编号 - Q96RI1
UniProt汇总 FUNCTION: SwissProt: Q96RI1 # Receptor for bile acids such as chenodeoxycholic acid, lithocholic acid and deoxycholic acid. Represses the transcription of the cholesterol 7-alpha-hydroxylase gene (CYP7A1) and activates the intestinal bile acid-binding protein (IBABP). Activates the transcription of bile salt export pump ABCB11 by directly recruiting histone methyltransferase CARM1 within its gene locus.
SIZE: 486 amino acids; 55914 Da
SUBUNIT: Heterodimer of NR1H4 and RXR. Interacts with CARM1 and SMARD1.
SUBCELLULAR LOCATION: Nucleus (Probable).
SIMILARITY: SwissProt: Q96RI1 ## Belongs to the nuclear hormone receptor family. NR1 subfamily. & Contains 1 nuclear receptor DNA-binding domain.产品使用声明 质量保证 Routinely evaluated by immunoblot. 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Maintain at 2-8°C for up to 12 months from date of receipt. 包装信息 数量 100 µL
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