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merck millipore,默克密理博,05-857,Anti-phospho-Src family (Tyr416) Antibody, clone 2N8, rabbit monoclonal
产品名称：Anti-phospho-Src family (Tyr416) Antibody, clone 2N8, rabbit monoclonal
产品型号：05-857
This Anti-phospho-Src family (Tyr416) Antibody, clone 2N8 is validated for use in WB for the detection of phospho-Src family (Tyr416).
merck millipore,默克密理博,05-857,Anti-phospho-Src family (Tyr416) Antibody, clone 2N8, rabbit monoclonal
- 产品介绍
- merck millipore,默克密理博,05-857,Anti-phospho-Src family (Tyr416) Antibody, clone 2N8, rabbit monoclonal
重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 Vrt, M WB Rb Purified Monoclonal Antibody 描述 产品目录编号 05-857 Replaces 16-249 品牌系列 Upstate
商名 - Upstate
描述 Anti-phospho-Src family (Tyr416) Antibody, clone 2N8, rabbit monoclonal Alternate Names - KAT13A
产品信息 格式 Purified 应用 应用 This Anti-phospho-Src family (Tyr416) Antibody, clone 2N8 is validated for use in WB for the detection of phospho-Src family (Tyr416). 主要应用 - Western Blotting
生物信息 免疫原品种 synthetic peptide containing the sequence ...NE[pY]TA, where pY corresponds to phosphotyrosine at position 416 of c-Src. 克隆 2N8 宿主 Rabbit 特异性 phospho-c-Src (Tyr416) 同种型 IgG 品种反应性 VertebratesMouse 抗体类型 Monoclonal Antibody Entrez基因编号 - NM_005417
Entrez基因汇总 This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. The protein encoded by this gene is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-SRC kinase. Mutations in this gene could be involved in the malignant progression of colon cancer. Two transcript variants encoding the same protein have been found for this gene. 基因符号 - pp60c-src
- SRC
- c-src
- p60-Src
- SRC1
- c-SRC
- ASV
修改 - Phosphorylation
纯化方法 Protein A purfied UniProt编号 - P12931
UniProt汇总 SIZE: 536 amino acids; 59835 Da
SUBUNIT: Interacts with DDEF1/ASAP1 via its SH3 domain. Interacts with CCPG1 (By similarity). Interacts with CDCP1, PELP1, TGFB1I1 and TOM1L2.
PTM: Phosphorylated on Tyr-530 by c-Src kinase (CSK). The phosphorylated form is termed pp60c-src. The phosphorylated tail interacts with the SH2 domain thereby repressing kinase activity.
SIMILARITY: SwissProt: P12931 ## Belongs to the protein kinase superfamily. Tyr protein kinase family. SRC subfamily. & Contains 1 protein kinase domain. & Contains 1 SH2 domain. & Contains 1 SH3 domain.产品使用声明 质量保证 Routinely evaluated by immunoblot of endogenous phospho-c-Src immunoprecipitated from NIH/3T3 RIPA lysates with anti-Src, clone GD11 agarose beads (Cat # 16-186) 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 2 years at -20°C from date of shipment 包装信息 数量 100 µL
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